RHO - rhodopsin Gene

Also Known as RP4; OPN2; CSNBAD1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6010

About RHO

Cytogenetic location: 3q22.1 Genomic coordinates (GRCh38): 3:129,528,639-129,535,344 (from NCBI)

This gene has 1 transcript (splice variant), 276 orthologues, 9 paralogues and is associated with 8 phenotypes. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness. [provided by RefSeq, Aug 2017]

RHO Products (1)

mRNA	Protein	Name
NM_000539.3	NP_000530.1	rhodopsin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12754272	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	2218504	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in Golgi apparatus	IDA IDA: Inferred from direct assay	11767049	GOA
located in photoreceptor disc membrane	IDA IDA: Inferred from direct assay	25664179	GOA
located in photoreceptor inner segment	IDA IDA: Inferred from direct assay	11767049	GOA
located in photoreceptor inner segment membrane	IDA IDA: Inferred from direct assay	19934218	GOA
located in photoreceptor outer segment	IDA IDA: Inferred from direct assay	11767049	GOA
located in photoreceptor outer segment membrane	IDA IDA: Inferred from direct assay	19934218	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	31380578	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RHO Protein Structure

Rhodopsin_N

7tm_1

0
100
200
300
348 a.a.

Protein Preferred Names	Protein Names
rhodopsin	opsin 2, rod pigment

RHO Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	RHO	P08100	ZFYVE9	Homo sapiens	O95405	Pull Down	17693260
Intra	RHO	P08100	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
Intra	RHO	P08100	CD79A	Homo sapiens	P11912	Validated Y2H	32296183
Intra	RHO	P08100	CD79A	Homo sapiens	P11912	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

RHO Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83524	Rhodopsin Antibody (YA3269)	WB, IHC-P	Human, Rat

Related Diseases

Diseases	Alias
Retinitis Pigmentosa 4	RP4 Retinitis Pigmentosa 4, Autosomal Dominant Or Recessive Retinitis Pigmentosa, Rhodopsin-Related Retinitis Pigmentosa, Type 4
Night Blindness, Congenital Stationary, Autosomal Dominant 1	Congenital Stationary Night Blindness Autosomal Dominant 1 CSNBAD1 Rhodopsin-Related Congenital Stationary Night Blindness Night Blindness, Congenital Stationary, Rhodopsin-Related Blindness, Night, Stationary, Congenital, Autosomal Dominant, Type 1
Fundus Albipunctatus	Retinitis Punctata Albescens Pigmentary Retinal Dystrophy RPA Albipunctate Retinal Dystrophy Lauber'S Disease FALBI Fa
Night Blindness	Nyctalopia
Optic Disk Drusen	Optic Disc Drusen Drusen Of Optic Disc Optic Nerve Head Drusen Drusen Optic Disc
Retinal Detachment	Retinal Detachments Rhegmatogenous Retinal Detachment Ruptured Retina With Detachment Retinal Hole With Detachment
Coats Disease	Exudative Retinopathy Retinal Telangiectasis Coats' Disease Leber Miliary Aneurysm Coats' Syndrome Congenital Retinal Telangiectasia
Neuropathy, Congenital Hypomyelinating, 2	Hypomyelinating Neuropathy, Congenital, 2 CHN2
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Cataract	Cataracts Cat - [Cataract] Cataract Form Lens Opacity Lens Opacities
Fundus Dystrophy	Retinal Dystrophy Retinal Dystrophies Dystrophy, Retinal
Congenital Stationary Night Blindness	Night Blindness, Congenital Stationary Congenital Essential Nyctalopia Oguchi Disease Blindness, Night, Stationary, Congenital
Cone-Rod Dystrophy 2	Cone-Rod Dystrophy CORD2 Cone-Rod Retinal Dystrophy Rcrd2 Cone-Rod Retinal Dystrophy 2 Crd2 Cord Crd Retinal Cone-Rod Dystrophy Cone-Rod Retinal Dystrophy-2 Retinal Cone-Rod Dystrophy 2 Tapetoretinal Degeneration Cone-Rod Degeneration Cone Rod Dystrophy Dystrophy, Cone-Rod Dystrophy, Cone-Rod, Type 2 Retinitis Pigmentosa Retinitis Pigmentosa 2 Progressive Cone-Rod Dystrophy
Retinitis
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Hereditary Retinal Dystrophy	Hereditary Retinal Dystrophies
Retinitis Pigmentosa 1	RP1 Retinitis Pigmentosa-1 Retinitis Pigmentosa, Type 1
Xerophthalmia	Conjunctival Xerosis
Oguchi Disease	Stationary Night Blindness, Oguchi Type Congenital Stationary Night Blindness, Oguchi Type Oguchi Syndrome Oguchis Disease
Keratomalacia	Vitamin A Deficiency Night Blindness Retinol Deficiency Xerotic Keratitis VAD Vitamin A Hypovitaminosis A Bitot Spots Bitot Spots In The Young Child Conjunctival Xerosis With Bitot'S Spots Vitamin A Deficiency With Cornea Xerosis Vitamin A Deficiency With Cornea Ulceration Or Xerosis
Retinal Degeneration	Degeneration Of Retina
Eye Degenerative Disease
Ocular Hypertension	Hypertension, Ocular Intraocular Pressure Increase Oh - [Ocular Hypertension] Oht - [Ocular Hypertension]
Myopia	Near-Sightedness Short-Sightedness Nearsightedness Nearsighted Near Vision Close Sighted Myopic Short-Sighted Near Sighted
Solar Retinopathy	Solar Retinitis
Stargardt Disease	Stargardt Disease 1 Stargardt Macular Dystrophy Stargardt Disease-1 Juvenile Onset Macular Degeneration Stargardt Macular Degeneration Juvenile Macular Degeneration Macular Dystrophy With Flecks, Type 1 Stgd Fundus Flavimaculatus Stargardt 1 Stargardts Disease
Macular Degeneration, Age-Related, 1	Macular Degeneration Age-Related Macular Degeneration Macular Degeneration, Age-Related Age Related Macular Degeneration Age Related Macular Degeneration 1 ARMD1 Senile Macular Degeneration Maculopathy, Age-Related, 1 Macular Degeneration, Age-Related, Reduced Risk Of Age Related Maculopathy 1 Age Related Maculopathies Age Related Maculopathy Senile Macular Retinal Degeneration Macular Degeneration Of Retina Age-Related Maculopathy Amd Armd Age-Related Maculopathy, Susceptibility To Maculopathy Age-Related Macular Degeneration, Age-Related, 1, Susceptibility To Maculopathy, Age-Related Macular Degeneration, Age-Related, Type 1 Macular Degeneration, Age-Related, 2
Retinoschisis 1, X-Linked, Juvenile	Retinoschisis X-Linked Retinoschisis X-Linked Juvenile Retinoschisis RS1 XLRS1 X-Linked Juvenile Retinoschisis 1 Xlrs Retinoschisis, X-Linked Rs Congenital X-Linked Retinoschisis Degenerative Retinoschisis Juvenile Retinoschisis Xjr Retinoschisis Juvenile X-Linked 1 Retinoschisis, Juvenile, X-Linked Retinoschisis, Degenerative
Oguchi Disease 1	Oguchi Disease-1 CSNBO1 Night Blindness, Congenital Stationary, Oguchi Type 1 Congenital Stationary Night Blindness Oguchi Type 1 Oguchi Disease
Oguchi Disease 2	Oguchi Disease-2 CSNBO2 Night Blindness, Congenital Stationary, Oguchi Type 2 Congenital Stationary Night Blindness Oguchi Type 2
Degeneration Of Macula And Posterior Pole	Degeneration Of Macula And Posterior Pole Of Retina Degeneration Of Macula Or Posterior Pole Macular Degeneration Nos Degenerative Disorder Of Macula Drusen Macular Degeneration Posterior Pole Macular Degeneration Of Eye Macular Eye Degeneration Macular Degeneration Of Retina, Unspecified Pseudohole Degeneration Of Macula Of Retina
Refractive Error	Refractive Errors
Chorioretinal Scar	Chorioretinal Cicatrix Cicatrix Of Choroid Choroid Scar Macula Scar Macular Scarring Retinal Cicatrix Retinal Scar
Cholera	Vibrio Cholerae Infection Cholera - Vibrio Cholerae Cholera Due To Vibrio Cholerae Vibrio Cholerae Cholera Syndrome Asiatic Cholera Epidemic Cholera
Leber Congenital Amaurosis 2	LCA2 Amaurosis Congenita Of Leber Ii Amaurosis Congenita Of Leber, Type 2 Leber Congenital Amaurosis Type Ii Leber Congenital Amaurosis, Type 2 Leber Congenital Amaurosis, Type Ii
Pineocytoma	Pinealoma Pinealocytoma Pineal Gland Neoplasm Tumor Of The Pineal Region
Enhanced S-Cone Syndrome	Goldmann-Favre Syndrome ESCS Favre Hyaloideoretinal Degeneration Retinoschisis With Early Hemeralopia Retinoschisis With Early Nyctalopia Enhanced S Cone Syndrome S-Cone Syndrome, Enhanced
Myasthenic Syndrome, Congenital, 3a, Slow-Channel	Congenital Myasthenic Syndrome 3a CMS3A Congenital Myasthenic Syndrome 3a, Slow-Channel Myasthenic Syndrome, Congenital, Type 3a, Slow-Channel
Leber Plus Disease	Leber Congenital Amaurosis Lca Leber'S Amaurosis Leber'S Disease Amaurosis Congenita Of Leber Amaurosis Congenita Of Leber, Type 1 Lhon Plus Disease Congenital Absence Of The Rods And Cones Congenital Retinal Blindness Crb Congenital Amaurosis Of Retinal Origin Leber'S Congenital Amaurosis Leber Congenital Amaurosis 1 Leber'S Congenital Tapetoretinal Degeneration Leber'S Congenital Tapetoretinal Dysplasia Lca1 Leber Congenital Amaurosis Type 1 Retinal Blindness, Congenital Amaurosis, Leber Congenital Dysgenesis Neuroepithelialis Retinae Hereditary Epithelial Dysplasia Of Retina Hereditary Retinal Aplasia Heredoretinopathia Congenitalis Leber Abiotrophy Leber Congenital Tapetoretinal Degeneration Lebers Congenital Amaurosis Optic Atrophy, Hereditary, Leber
Microvascular Complications Of Diabetes 5	Diabetic Retinopathy Microvascular Complications Of Diabetes, Susceptibility To, 5 MVCD5 Retinopathy, Diabetic Diabetic Nephropathy Retinopathy, Diabetic, Susceptibility To Retinal Abnormality - Diabetes-Related
Retinal Perforation	Retinal Break Retinal Perforations Retinal Dialysis Retinal Tear Retinal Break Nos Ruptured Retina
Retinal Disease	Retinal Diseases Retinal Disorder Retinal Disorders
Macular Dystrophy, Dominant Cystoid	Cystoid Macular Edema DCMD Cystoid Macular Dystrophy Macular Edema, Cystoid Autosomal Dominant Cystoid Macular Edema Cymd Mddc Familial Macular Edema Macular Edema Macular Retinal Edema
Red-Green Color Blindness	Deutan Defect Deuteranopia Reduced Red-Green Discrimination Color Blindness, Red-Green Colorblindness, Partial, Deutan Series
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Scotoma	Enlarged Blind Spot Scotoma Of Blind Spot Area Blind Spot Area Scotoma Enlarged Angioscotoma Enlarged Paracaecal Scotoma Generalized Visual Field Contraction Or Constriction Sector Or Arcuate Visual Field Defects
Glucocorticoid Deficiency 1	Acth Resistance Glucocorticoid Deficiency, Due To Acth Unresponsiveness GCCD1 Familial Glucocorticoid Deficiency 1 Fgd1 Adrenal Unresponsiveness To Acth Hereditary Unresponsiveness To Adrenocorticotropic Hormone Isolated Glucocorticoid Deficiency
Peripheral Retinal Degeneration	Peripheral Degeneration Of Retina Degeneration Of Retina Nos Reticular Retinal Degeneration Retinal Degeneration
Choroid Disease	Choroid Diseases Abnormality Of The Choroid
Late-Onset Retinal Degeneration	LORD Retinal Degeneration, Late-Onset, Autosomal Dominant Autosomal Dominant Late-Onset Retinal Degeneration Pigmentary Retinopathy Retinal Degeneration, Late-Onset Retinitis Pigmentosa
Color Blindness	Color Vision Defect Blindness Color Colour Blindness Colour Vision Deficiency Color Vision Deficiency Color Vision Defects Defective Color Vision Vision Defect, Color Color-Vision Disease Dyschromatopsia
Sensory System Disease
Glaucoma, Primary Open Angle	Glaucoma 1, Open Angle, E Primary Open Angle Glaucoma POAG Adult-Onset Primary Open Angle Glaucoma Chronic Simple Glaucoma GLC1E Primary Open Angle Glaucoma 1e Glaucoma, Open Angle, Primary
Achromatopsia	Achm Rod Monochromatism Total Color Blindness Rod Monochromacy Monochromatism Achromatism Complete Or Incomplete Color Blindness Pingelapese Blindness Achromatopsia 1 Achromatopsia 2 Achromatopsia 3
Vitreous Disease	Disorder Of Vitreous Body
Macular Retinal Edema	Macular Edema Macular Oedema Macular Retinal Oedema Macular Edema, Cystoid
Sorsby Fundus Dystrophy	SFD Fundus Dystrophy, Pseudoinflammatory, Of Sorsby Sorsby'S Fundus Dystrophy Macular Dystrophy, Hemorrhagic Hemorrhagic Macular Dystrophy Pseudoinflammatory Fundus Dystrophy Of Sorsby Sorsby'S Pseudoinflammatory Macular Dystrophy Sorsby Pseudoinflammatory Fundus Dystrophy Dystrophy, Fundus, Sorsby
Colorblindness, Partial, Protan Series	Protanopia Red Color Blindness Protan Defect CBP Red Colorblindness Colorblindness, Protan Color Blindness, Red
Vitelliform Macular Dystrophy	Best Disease Juvenile-Onset Vitelliform Macular Dystrophy Macular Dystrophy, Vitelliform Best Macular Dystrophy Vitelliform Dystrophy
Leber Congenital Amaurosis 10	LCA10 Leber Congenital Amaurosis, Type 10
Gyrate Atrophy Of Choroid And Retina	Gyrate Atrophy Ornithine Aminotransferase Deficiency HOGA Hyperornithinemia With Gyrate Atrophy Of Choroid And Retina Oat Deficiency Okt Deficiency Hyperornithinemia Ornithine Keto Acid Aminotransferase Deficiency Ornithine-Delta-Aminotransferase Deficiency Gyrate Atrophy Of The Choroid And Retina GACR Gyrate Atrophy Of Choroid And Retina With Or Without Ornithinemia Gyrate Atrophy Of The Retina Ornithinemia With Gyrate Atrophy Ornithinemia Fuchs Atrophia Gyrata Chorioideae Et Retinae Hyperornithinemia-Gyrate Atrophy Of Choroid And Retina Syndrome Gyrate Atrophy Of The Choroid And/Or Retina Girate Atrophy Of The Retina Ornithine Ketoacid Aminotransferase Deficiency Atrophy, Gyrate, Of Choroid And Retina
Exudative Vitreoretinopathy 1	Retinopathy Of Prematurity Retrolental Fibroplasia EVR1 Criswick-Schepens Syndrome Rop Exudative Vitreoretinopathy, Familial, Autosomal Dominant Fevr, Autosomal Dominant Premature Retinopathy Vitreoretinopathy, Exudative 1 Autosomal Dominant Familial Exudative Vitreoretinopathy Fevr Vitreoretinopathy, Exudative, Type 1 Retinopathy Of Prematurity Nos Rlf- [Retrolental Fibroplasia] Rop - [Retinopathy Of Prematurity] Terry Syndrome
Prolonged Electroretinal Response Suppression	Bradyopsia PERRS
Cone Dystrophy	Retinal Cone Dystrophy Dystrophy, Cone Cone Dystrophy 3
X-Linked Nephrogenic Diabetes Insipidus	Nephrogenic Diabetes Insipidus Type 1 Doid:0081060
Choroideremia	CHM Tcd Progressive Tapetochoroidal Dystrophy Choroidal Sclerosis Tapetochoroidal Dystrophy, Progressive Progressive Choroidal Atrophy Tapetochoroidal Dystrophy
Retinitis Pigmentosa 2	RP2 X-Linked Retinitis Pigmentosa 2 Xlrp2 Xlrp-2 Retinitis Pigmentosa-2 Retinitis Pigmentosa, Type 2
Lens Disease	Lens Diseases
Retinal Vascular Occlusion	Retinal Vasc. Occlusion Occlusion Of Retinal Vessels Retinal Obstruction
Retinal Ischemia
Nephrogenic Diabetes Insipidus	Vasopressin-Resistant Diabetes Insipidus Diabetes Insipidus, Nephrogenic Diabetes Insipidus Nephrogenic Congenital Nephrogenic Diabetes Insipidus Adh Resistant Diabetes Insipidus Diabetes Insipidus Nephrogenic X-Linked Diabetes Insipidus Nephrogenic Type 1 Adh-Resistant Diabetes Insipidus Diabetes Insipidus Renalis Ndi Renal Diabetes Insipidus Familial Nephrogenic Diabetes Antidiuretic-Hormone-Resistant Diabetes Insipidus Adiuretin-Resistant Diabetes Insipidus Ndi - [Nephrogenic Diabetes Insipidus] Diabetes Tenuifluus Adh - [Antidiuretic-Hormone] Resistant Diabetes Insipidus Hereditary Nephrogenic Diabetes Insipidus Familial Nephrogenic Diabetes Insipidus Primary Nephrogenic Diabetes Insipidus
Usher Syndrome Type 2	Ush2 Usher Syndrome Type Ii
Retinal Vascular Disease	Retinal Vascular Retinal Vascular Disorder Retina Circulation Disorder
Meckel Syndrome, Type 1	Meckel-Gruber Syndrome Meckel Syndrome Dysencephalia Splanchnocystica Meckel Syndrome 1 MKS1 Mks Gruber Syndrome Meckel-Gruber Syndrome, Type 1 Mes Dysencephalia Splachnocystica Meckel Gruber Syndrome Meckel Syndrome Type 1
Usher Syndrome	Deafness-Retinitis Pigmentosa Syndrome Dystrophia Retinae Pigmentosa-Dysostosis Syndrome Graefe-Usher Syndrome Hallgren Syndrome Usher'S Syndrome Retinitis Pigmentosa-Deafness Syndrome Retinitis Pigmentosa-Hearing Loss Syndrome Ush Usher Syndromes
Retinitis Pigmentosa 26	RP26 Retinitis Pigmentosa-26 Retinitis Pigmentosa, Type 26
Uveal Disease	Uveal Diseases
Transient Refractive Change
Retinitis Pigmentosa 7	Leber Congenital Amaurosis 18 RP7 Retinitis Pigmentosa 7, Digenic Form Retinitis Pigmentosa 7 And Digenic Form Retinitis Pigmentosa 7, Digenic LCA18 Retinitis Pigmentosa 7 Digenic
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Nanophthalmos	Nanophthalmia
Usher Syndrome, Type I	USH1 Usher Syndrome Type 1 Us1 Usher Syndrome, Type 1b Usher Syndrome Type 1e Retinitis Pigmentosa And Congenital Deafness Usher Syndrome, Type Ie USH1E Usher Syndrome, Type 1e Usher Syndrome, Type 1a Usher Syndrome, Type Ib Usher Syndrome Type 1b Usher Syndrome Type Ie Usher Syndrome Type I Usher 1 Usher Syndrome, Type 1 Ush1a Usher Syndrome, Type I, French Variety Usher Syndrome, Type Ia Usher Syndrome 1b USH1B Usher'S Syndrome Type 1b Usher Syndrome Type Ib Ushib
Senior-Loken Syndrome 1	Senior-Loken Syndrome Renal Dysplasia And Retinal Aplasia Renal-Retinal Syndrome Loken-Senior Syndrome Juvenile Nephronophthisis With Leber Amaurosis SLSN1 Senior-Loken Syndrome-1 Loken Senior Syndrome Senior Loken Syndrome Renal Dysplasia Retinal Aplasia Nephronophthisis With Retinal Dystrophy Renal Dysplasia-Retinal Aplasia Syndrome Slsn
Nephronophthisis	Medullary Cystic Disease Medullary Cystic Kidney Nph Nphp Kidney Disease, Cystic, Medullary
Joubert Syndrome 1	Joubert Syndrome Jbts Cerebellooculorenal Syndrome 1 JBTS1 Joubert-Boltshauser Syndrome Cerebelloparenchymal Disorder Iv Cpd4 Cors1 Joubert Syndrome And Related Disorders Jsrd Familial Aplasia Of The Vermis Joubert Syndrome Related Disorders Js Cerebellar Vermis Agenesis Cerebelloparenchymal Disorder 4 Agenesis Of Cerebellar Vermis Cerebello-Oculo-Renal Syndrome Cors Joubert-Bolthauser Syndrome Cpd Iv Classic Joubert Syndrome Joubert Syndrome Type A Pure Joubert Syndrome Cerebello-Oculo-Renal Syndrome 1 Joubert Syndrome-1 Joubert Syndrome, Type 1 Joubert'S Syndrome
Bardet-Biedl Syndrome	Bbs Biedl-Bardet Syndrome
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10583	Y-27632 dihydrochloride	Inhibitor	99.98%	Unkown
HY-10583R	Y-27632 dihydrochloride (Standard)	Inhibitor	99.99%	Unkown
HY-12798	Netarsudil	Inhibitor	99.94%	Unkown
HY-12798B	Netarsudil hydrochloride	Inhibitor	99.90%	Unkown
HY-B0515	Ibandronate Sodium Monohydrate	Inducer	99.89%	Unkown
HY-12798A	Netarsudil dimesylate		99.90%	Unkown
HY-19518	Latanoprostene bunod	Control	99.75%	Unkown
HY-B0515B	Ibandronate Sodium	Inducer	99.89%	Unkown

Clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Phase
HY-109191	Sovesudil	Inhibitor	99.91%	Phase 3
HY-109191A	Sovesudil hydrochloride	Inhibitor	99.45%	Phase 3
HY-113225B	Guanosine triphosphate tritris	Inducer	/	Phase 3
HY-148808	Zelasudil	Inhibitor	99.48%	Phase 2
HY-I0400	N-Acetylneuraminic acid		99.95%	Phase 1

Pre-clinical Phase

Bioactive Molecules (80)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15392	Chroman 1	Inhibitor	98.97%	Unkown
HY-12755	ML141		99.96%	Unkown
HY-12646	Rhosin hydrochloride		99.94%	Unkown
HY-10583G	Y-27632 dihydrochloride (GMP)	Inhibitor	/	Unkown
HY-16563	Narciclasine	Activator	99.88%	Unkown
HY-17543	ML-323	Inhibitor	99.51%	Unkown
HY-12646A	Rhosin		98.74%	Unkown
HY-13991	CCG-1423		99.88%	Unkown
HY-108361	CCG-203971	Inhibitor	99.89%	Unkown
HY-104064	1A-116		99.72%	Unkown
HY-12649	Y16	Inhibitor	98.12%	Unkown
HY-115376	Z62954982	Inhibitor	99.38%	Unkown
HY-N6012	(-)-Alkannin	Inducer	99.88%	Unkown
HY-111458	GSK2643943A	Inhibitor	98.79%	Unkown
HY-121750	CCG-222740	Inhibitor	99.53%	Unkown
HY-134817	USP7-IN-8	Inhibitor	99.04%	Unkown
HY-N2438	Methylophiopogonanone B		99.84%	Unkown
HY-108518	SB-772077B dihydrochloride	Inhibitor	99.33%	Unkown
HY-15392A	Chroman 1 dihydrochloride	Inhibitor	98.13%	Unkown
HY-18990	GSK180736A	Inhibitor	98.81%	Unkown
HY-32951	2-Fluoropyridine-4-boronic acid		99.78%	Unkown
HY-112362	3-(4-Pyridyl)indole	Inhibitor	99.94%	Unkown
HY-N0430A	Coptisine Sulfate		99.37%	Unkown
HY-111432	CCG-232601	Inhibitor	99.00%	Unkown
HY-139170	CAY10746	Inhibitor	98.61%	Unkown
HY-117149	MLS000532223	Inhibitor	98.45%	Unkown
HY-N0600	Ginsenoside F3		99.84%	Unkown
HY-150640	Rho-Kinase-IN-2	Inhibitor	98.80%	Unkown
HY-W050122	S-(+)-GABOB		95.0%	Unkown
HY-100270	Rho-Kinase-IN-1	Inhibitor	99.91%	Unkown
HY-100062	2,4-Dibromo-5-nitropyridine		/	Unkown
HY-122011	PF-4950834	Inhibitor	99.60%	Unkown
HY-126432	NRL-1049 dihydrochloride	Inhibitor	99.20%	Unkown
HY-15720B	Glycyl H-1152 hydrochloride	Inhibitor	99.9%	Unkown
HY-126913	Rhodblock 6	Inhibitor	98.94%	Unkown
HY-152095	PPI-GIT1/β-Pix PPI-IN-1	Inhibitor	99.01%	Unkown
HY-N0430	Coptisine		/	Unkown
HY-P2325	Exoenzyme C3, clostridium botulinum	Inhibitor	/	Unkown
HY-118151	Rho-Kinase-IN-3	Inhibitor	99.74%	Unkown
HY-103045A	CMPD101 hydrochloride	Inhibitor	/	Unkown
HY-107614G	1-Oleoyl lysophosphatidic acid sodium (GMP)	Activator	/	Unkown
HY-118046	GSK2163632A	Inhibitor	/	Unkown
HY-118837	WF-536	Inhibitor	/	Unkown
HY-120429	SKLB-163	Inducer	/	Unkown
HY-123345	CRT 0105446	Inhibitor	/	Unkown
HY-129907	2-AEMP		/	Unkown
HY-130011	CCG-232964	Inhibitor	/	Unkown
HY-132184S	5,6-Epoxyeicosatrienoic acid-d11		/	Unkown
HY-134913	Rhodblock 1a	Inhibitor	/	Unkown
HY-137638	Sp-5,6-DCl-cBIMPS	Activator	/	Unkown
HY-137638A	Sp-5,6-DCl-cBIMPS sodium	Activator	/	Unkown
HY-138147	DCP-Rho1		/	Unkown
HY-13991A	(S)-CCG-1423		/	Unkown
HY-145294	ROCK2-IN-5	Inhibitor	/	Unkown
HY-171909	Glycerophosphoinositol 4-phosphate		/	Unkown
HY-171909A	Glycerophosphoinositol 4-phosphate disodium		/	Unkown
HY-172917	Rho GTPase inhibitor 1	Inhibitor	/	Unkown
HY-173222	P-gp inhibitor 28	Inhibitor	/	Unkown
HY-180371	NF-115	Inducer	/	Unkown
HY-182613	NSC-2888		/	Unkown
HY-185667	ROCK2-IN-15	Inhibitor	/	Unkown
HY-D3474	ATTO Rho 101 NHS ester		/	Unkown
HY-D3475	ATTO Rho 11 NHS ester		/	Unkown
HY-N10341	Centaureidin	Activator	/	Unkown
HY-P11847	AT1R-agonist-1		/	Unkown
HY-P5158	Conopeptide rho-TIA	Inhibitor	/	Unkown
HY-P5467	S6(229-239), Amide, biotinalyted	Substrate	/	Unkown
HY-RS11944	RHO Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS11951	RHOD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W047432	5-Nitro-1H-indazole-3-carbonitrile	Inhibitor	/	Unkown
HY-W110138	Chloroxoquinoline		/	Unkown
HY-123939	JAK1/3-IN-1	Inhibitor	/	Unkown
HY-130448	8-iso Prostaglandin F1β		/	Unkown
HY-158652	(R)-CCG-1423	Inhibitor	/	Unkown
HY-183451	Y-30141	Inhibitor	/	Unkown
HY-P10393	ERα17p	Inducer	/	Unkown
HY-P10636	Nictide		/	Unkown
HY-RS17157	Rho Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22304	Rhod Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23607	Rho Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	RHO	VGNC	VGNC:110341
Bos taurus	RHO	VGNC	VGNC:33942
Felis catus	RHO	VGNC	VGNC:64612
Mus musculus	RHO	MGD	MGI:97914
Rattus norvegicus	RHO	RGD	RGD:3573
Canis familiaris	RHO	VGNC	VGNC:45554
Others	RHO	NCBI