1. Cell Cycle/DNA Damage
    TGF-beta/Smad
    Stem Cell/Wnt
  2. ROCK
  3. Rho-Kinase-IN-1

Rho-Kinase-IN-1 

Cat. No.: HY-100270
Handling Instructions

Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor (Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1.008.

For research use only. We do not sell to patients.

Rho-Kinase-IN-1 Chemical Structure

Rho-Kinase-IN-1 Chemical Structure

CAS No. : 1035094-83-7

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Description

Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor (Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1.008[1].

IC50 & Target[1]

ROCK1

30.5 nM (Ki)

ROCK2

3.9 nM (Ki)

In Vitro

Rho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases or conditions associated with excessive cell proliferation, remodeling, edema and inflammation[1].

Molecular Weight

352.50

Formula

C₂₀H₂₄N₄S

CAS No.

1035094-83-7

SMILES

CSC1=CC=C(CN2CC(NC3=CC4=C(NN=C4)C=C3)CCC2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Rho-Kinase-IN-1
Cat. No.:
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