DUSP21 - dual specificity phosphatase 21 Gene

Also Known as LMWDSP21

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 63904

Summary

This gene encodes a member of the dual specificity Phosphatase family, specifically the low molecular weight dual specificity Phosphatase family. The encoded protein localizes to both the cytoplasm and the nucleus and functions to remove phosphate groups from phosphotyrosine and phosphothreonine residues.[provided by RefSeq, Mar 2009]

DUSP21 Products (1)

mRNA Protein Name
NG_013231.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
12408986 GOA
Biological Process GO Annotation Evidence References Source
involved in peptidyl-tyrosine dephosphorylation IDA
IDA: Inferred from direct assay
12408986 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12408986 GOA
located in nucleus IDA
IDA: Inferred from direct assay
12408986 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DUSP21 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DUSP21 Q9H596 CTBP2 Homo sapiens P56545-3
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 CTBP2 Homo sapiens P56545-3
Y2H Array
32296183
Intra
DUSP21 Q9H596 KRT33B Homo sapiens Q14525
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 KRT33B Homo sapiens Q14525
Y2H Array
32296183
Intra
DUSP21 Q9H596 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Array
32296183
Intra
DUSP21 Q9H596 KLHL20 Homo sapiens Q9BS75
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 KLHL20 Homo sapiens Q9BS75
Y2H Array
32296183
Intra
DUSP21 Q9H596 TEX11 Homo sapiens Q8IYF3-3
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 CPNE7 Homo sapiens Q9UBL6-2
Validated Y2H
32296183
Intra
DUSP21 Q9H596 EYA2 Homo sapiens O00167-2
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 EYA2 Homo sapiens O00167-2
Y2H Array
32296183
Intra
DUSP21 Q9H596 ATP23 Homo sapiens Q9Y6H3
Validated Y2H
32296183
Intra
DUSP21 Q9H596 ATP23 Homo sapiens Q9Y6H3
Y2H Array
32296183
Intra
DUSP21 Q9H596 ATP23 Homo sapiens Q9Y6H3
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 TRAF1 Homo sapiens Q13077
Y2H Array
32296183
Intra
DUSP21 Q9H596 OIP5 Homo sapiens O43482
Y2H Array
32296183
Intra
DUSP21 Q9H596 OIP5 Homo sapiens O43482
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 GET4 Homo sapiens Q7L5D6
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 GET4 Homo sapiens Q7L5D6
Y2H Array
32296183
Intra
DUSP21 Q9H596 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
25416956
Intra
DUSP21 Q9H596 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
32296183
Intra
DUSP21 Q9H596 GORASP2 Homo sapiens Q9H8Y8
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
32296183
Intra
DUSP21 Q9H596 TEX11 Homo sapiens Q8IYF3
Y2H Prey Pooling
25416956
Intra
DUSP21 Q9H596 RFX6 Homo sapiens Q8HWS3
Y2H Array
32296183
Intra
DUSP21 Q9H596 RFX6 Homo sapiens Q8HWS3
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
DUSP21 Q9H596 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
DUSP21 Q9H596 BPIFA1 Homo sapiens Q9NP55
Y2H Array
32296183
Intra
DUSP21 Q9H596 BPIFA1 Homo sapiens Q9NP55
Y2H Prey Pooling
32296183
Intra
DUSP21 Q9H596 BPIFA1 Homo sapiens Q9NP55
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04060 DUSP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04050 DUSP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04052 DUSP11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04053 DUSP12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04061 DUSP22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04062 DUSP23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04063 DUSP26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15532 USP21 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16828 Dusp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17277 Usp21 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19430 Dusp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23270 Dusp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23731 Usp21 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25921 Dusp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown