NABP1 - nucleic acid binding protein 1 Gene

Homo sapiens

Also known as SSB2; OBFC2A; SOSS-B2; NABP1-OT1

Gene ID: 64859 | Gene type: protein coding

About NABP1

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:191,678,136-191,686,943 (from NCBI)

This gene has 16 transcripts (splice variants), 205 orthologues, 1 paralogue and is associated with 1 phenotype. Broad expression in appendix (RPKM 17.5), spleen (RPKM 12.9) and 21 other tissues.

Summary

Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2A, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008]

NABP1 Products(2)

mRNA	Protein	Name
NM_001031716.5	NP_001026886.1	SOSS complex subunit B2 isoform 1
NM_001254736.3	NP_001241665.1	SOSS complex subunit B2 isoform 2

NABP1 Protein Structure

tRNA_anti-codon

0
100
204 a.a.

Protein Preferred Names

Protein Names

SOSS complex subunit B2

NABP1 3'UTR overlapping transcript 1

Related Diseases

Diseases

Alias

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic	Acute Myeloblastic Leukemia Type 3
Aml M3	APL
Leukemia, Acute Promyelocytic, Somatic	Aml With T(15
17)(Q22	Q12)
(Pml/Raralpha) And Variants	Apml
Acute Myeloblastic Leukemia 3	Acute Myeloid Leukemia With T(15
17)(Q22	Q12)
(Pml/Raralpha) And Variants	Acute Myeloblastic Leukaemia Type 3
Acute Myeloid Leukaemia M3	Acute Myeloid Leukemia M3
Acute Promyelocytic Leukaemia	M3 Anll
Myeloid Leukemia, Acute, M3	Leukemia Promyelocytic Acute
Leukemia, Promyelocytic, Acute	Leukemia, Acute, Promyelocytic

Cholestasis, Intrahepatic, Of Pregnancy 3

ICP3	Cholestasis, Intrahepatic, Of Pregnancy, 3
Intrahepatic Cholestasis Of Pregnancy 3	Pregnancy Related Cholestasis 3
Cholestasis Of Pregnancy, Intrahepatic 3	Cholestasis, Intrahepatic, Of Pregnancy, Type 3

Splenic Manifestation Of Leukemia

Splenic Leukemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08998	NABP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NABP1	RGD	RGD:1306658
Bos taurus	NABP1	VGNC	VGNC:31859
Mus musculus	NABP1	MGD	MGI:1923258
Felis catus	NABP1	VGNC	VGNC:63706
Macaca mulatta	NABP1	VGNC	VGNC:75025

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