PROM1 - prominin 1 Gene

Also Known as RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8842

About PROM1

Cytogenetic location: 4p15.32 Genomic coordinates (GRCh38): 4:15,968,228-16,084,023 (from NCBI)

This gene has 22 transcripts (splice variants), 277 orthologues, 1 paralogue and is associated with 10 phenotypes. Broad expression in gall bladder (RPKM 15.7), stomach (RPKM 10.2) and 18 other tissues.

Summary

This gene encodes a pentaspan Transmembrane Glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of Cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

PROM1 Products (10)

mRNA Protein Name
NM_001145847.2 NP_001139319.1 prominin-1 isoform 2 precursor
NM_001145848.2 NP_001139320.1 prominin-1 isoform 2 precursor
NM_001145849.2 NP_001139321.1 prominin-1 isoform 7 precursor
NM_001145850.2 NP_001139322.1 prominin-1 isoform 6 precursor
NM_001145851.2 NP_001139323.1 prominin-1 isoform 5 precursor
NM_001145852.2 NP_001139324.1 prominin-1 isoform 4 precursor
NM_001371406.1 NP_001358335.1 prominin-1 isoform 2 precursor
NM_001371407.1 NP_001358336.1 prominin-1 isoform 4 precursor
NM_001371408.1 NP_001358337.1 prominin-1 isoform 4 precursor
NM_006017.3 NP_006008.1 prominin-1 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actinin binding IDA
IDA: Inferred from direct assay
18654668 GOA
enables cadherin binding IPI
IPI: Inferred from physical interaction
18654668 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
18654668 GOA
Biological Process GO Annotation Evidence References Source
involved in camera-type eye photoreceptor cell differentiation IMP
IMP: Inferred from mutant phenotype
18654668 GOA
involved in glomerular parietal epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
19092120 GOA
involved in photoreceptor cell maintenance IMP
IMP: Inferred from mutant phenotype
18654668 GOA
involved in podocyte differentiation IMP
IMP: Inferred from mutant phenotype
19092120 GOA
involved in positive regulation of nephron tubule epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16885410 GOA
involved in retina morphogenesis in camera-type eye IMP
IMP: Inferred from mutant phenotype
18654668 GOA
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
16809613 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
24556617 GOA
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
24556617 GOA
located in extracellular exosome IDA
IDA: Inferred from direct assay
21082674 GOA
located in photoreceptor outer segment membrane IDA
IDA: Inferred from direct assay
18654668 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
12042327 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PROM1 Protein Structure

Prominin

Prominin: Prominin (12 - 829)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 865 a.a.
Protein Preferred Names Protein Names

prominin-1

  • antigen AC133

PROM1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PROM1 O43490 HDAC6 Homo sapiens Q9UBN7
Ub Reconstruction
23084749
Intra
PROM1 O43490 HDAC6 Homo sapiens Q9UBN7
Anti Bait CoIP
23084749
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PROM1 Proteins

Cat. No. Product Name Accession Purity
HY-P78732 CD133/PROM1 Protein-VLP, Human (HEK293, His) O43490 (G20-H865) Purity analysis by SDS-PAGE is not available for VLP proteins.

PROM1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P80054 CD133 Antibody (YA808) WB, IHC-P, FC Human
HY-P80594 CD133 Antibody (YA809) WB Human
HY-P80594A CD133 Antibody (YA809)(PBS only) WB Human
HY-P83841 CD133 Antibody (YA3538) FC, ELISA Human
HY-P83841A CD133 Antibody (YA3538)(PBS only) FC, ELISA Human
HY-P85586 CD133 Antibody (YA5278) WB Human
HY-P86623 CD133 Antibody (YA6315) WB, IHC-P, ICC/IF, IP, ELISA Human

Related Diseases

Diseases Alias
Macular Dystrophy, Retinal, 2

  • MCDR2

  • Retinal Macular Dystrophy Type 2

  • Retinal Macular Dystrophy 2

  • Dystrophy, Macular, Retinal, Type 2
Cone-Rod Dystrophy 12

  • CORD12

  • Dystrophy, Cone-Rod, Type 12
Stargardt Disease 4

  • STGD4
Retinitis Pigmentosa 41

  • RP41

  • Retinal Degeneration, Autosomal Recessive, Prominin-Related

  • Retinal Degeneration Autosomal Recessive Prominin-Related

  • Retinitis Pigmentosa-41

  • Retinitis Pigmentosa, Type 41
Stargardt Disease

  • Stargardt Disease 1

  • Stargardt Macular Dystrophy

  • Stargardt Disease-1

  • Juvenile Onset Macular Degeneration

  • Stargardt Macular Degeneration

  • Juvenile Macular Degeneration

  • Macular Dystrophy With Flecks, Type 1

  • Stgd

  • Fundus Flavimaculatus

  • Stargardt 1

  • Stargardts Disease
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Leber Congenital Amaurosis 1

  • LCA1

  • Amaurosis Congenita Of Leber I

  • Lca

  • Retinal Blindness, Congenital

  • Crb

  • Leber Congenital Amaurosis Type I

  • Leber Congenital Amaurosis, Type 1

  • Amaurosis Congenita Of Leber, Type 1
Isolated Macular Dystrophy
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Stargardt Disease 1

  • Fundus Flavimaculatus

  • STGD1

  • Retinal Dystrophy, Early-Onset Severe

  • Macular Dystrophy With Flecks, Type 1

  • Stargardt'S Disease

  • Stgd

  • Macular Degeneration, Juvenile

  • Macular Degeneration Juvenile

  • FFM

  • Juvenile Macular Degeneration

  • Macular Dystrophy With Flecks Type 1

  • Early Onset And Severe Retinal Dystrophy
Usher Syndrome

  • Deafness-Retinitis Pigmentosa Syndrome

  • Dystrophia Retinae Pigmentosa-Dysostosis Syndrome

  • Graefe-Usher Syndrome

  • Hallgren Syndrome

  • Usher'S Syndrome

  • Retinitis Pigmentosa-Deafness Syndrome

  • Retinitis Pigmentosa-Hearing Loss Syndrome

  • Ush

  • Usher Syndromes
Leber Plus Disease

  • Leber Congenital Amaurosis

  • Lca

  • Leber'S Amaurosis

  • Leber'S Disease

  • Amaurosis Congenita Of Leber

  • Amaurosis Congenita Of Leber, Type 1

  • Lhon Plus Disease

  • Congenital Absence Of The Rods And Cones

  • Congenital Retinal Blindness

  • Crb

  • Congenital Amaurosis Of Retinal Origin

  • Leber'S Congenital Amaurosis

  • Leber Congenital Amaurosis 1

  • Leber'S Congenital Tapetoretinal Degeneration

  • Leber'S Congenital Tapetoretinal Dysplasia

  • Lca1

  • Leber Congenital Amaurosis Type 1

  • Retinal Blindness, Congenital

  • Amaurosis, Leber Congenital

  • Dysgenesis Neuroepithelialis Retinae

  • Hereditary Epithelial Dysplasia Of Retina

  • Hereditary Retinal Aplasia

  • Heredoretinopathia Congenitalis

  • Leber Abiotrophy

  • Leber Congenital Tapetoretinal Degeneration

  • Lebers Congenital Amaurosis

  • Optic Atrophy, Hereditary, Leber
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Retinal Degeneration

  • Degeneration Of Retina
Teratoma

  • Teratomas
Acute Leukemia

  • Stem Cell Leukaemia

  • Stem Cell Leukemia

  • Acute Leukemias

  • Acute Undifferentiated Leukemia

  • Undifferentiated Leukemia

  • Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission

  • Blast Cell Leukaemia

  • Blast Leukaemia

  • Blastic Leukaemia

  • Undifferentiated Leukaemia
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Retinoblastoma

  • RB

  • Trilateral Retinoblastoma

  • RB1

  • Retinoblastoma, Trilateral

  • Neuroblastoma Of Retina

  • Rb - Retinoblastoma

  • Eye Cancer, Retinoblastoma

  • Retinal Cancer

  • Retinal Tumor

  • Glioma, Retinal

  • Non-Hereditary Retinoblastoma

  • Childhood Cancer Retinoblastoma

  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms
Hemangioblastoma

  • Capillary Hemangioblastoma
Bile Duct Cancer

  • Bile Duct Carcinoma

  • Extrahepatic Bile Duct Carcinoma

  • Carcinoma Of Extrahepatic Bile Duct

  • Extrahepatic Bile Duct Cancer

  • Bile Duct Neoplasms

  • Bile Duct Tumor

  • Ca Extrahepatic Bile Ducts

  • Malignant Neoplasm Of The Extrahepatic Bile Duct

  • Bile Duct Extrahepatic Carcinoma

  • Malignant Tumor Of Extrahepatic Bile Duct
Inflammatory Bowel Disease 30

  • Inflammatory Bowel Disease 30

  • IBD30
Childhood Infratentorial Neoplasm

  • Pediatric Infratentorial Tumor
Hemangioma

  • Hemangiomas
Gastric Adenosquamous Carcinoma

  • Adenosquamous Carcinoma Of Stomach
Buerger Disease

  • Thromboangiitis Obliterans

  • Buerger'S Disease

  • Presenile Gangrene

  • Inflammatory Occlusive Peripheral Vascular Disease

  • Occlusive Peripheral Vascular Disease

  • Tao

  • Endarteritis Obliterans
Hepatoblastoma
Infratentorial Cancer

  • Infratentorial Neoplasms

  • Brain Neoplasm, Infratentorial

  • Malignant Infratentorial Tumors
Limb Ischemia
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Capillary Hemangioma

  • Infantile Hemangioma

  • Strawberry Nevus Of Skin

  • Cellular Hemangioma Of Infancy

  • Congenital Vascular Hamartoma

  • Congenital Vascular Naevus

  • Juvenile Hemangioma

  • Strawberry Haemangioma

  • Strawberry Nevus

  • Hemangioma Capillary

  • Hemangioma, Capillary

  • Hemangioma, Cavernous
Ichthyosis, Congenital, Autosomal Recessive 11

  • Autosomal Recessive Congenital Ichthyosis 11

  • Ichthyosis With Hypotrichosis, Autosomal Recessive

  • Arih

  • Ichthyosis And Follicular Atrophoderma With Hypotrichosis And Hypohidrosis

  • Autosomal Recessive Ichthyosis With Hypotrichosis

  • ARCI11

  • Ifah

  • Hypotrichosis-Congenital Ichthyosis Syndrome

  • Ichthyosis-Follicular Atrophoderma-Hypotrichosis Syndrome

  • Ichthyosis-Follicular Atrophoderma-Hypotrichosis-Hypohidrosis Syndrome

  • Ichthyosis-Hypotrichosis Syndrome

  • Ifah Syndrome

  • Ihs
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Leukemia, Acute Lymphoblastic

  • Acute Lymphoblastic Leukemia

  • ALL

  • Acute Lymphocytic Leukemia

  • Leukemia, Acute Lymphocytic, Susceptibility To, 1

  • Acute Lymphoblastic Leukaemia

  • Precursor Lymphoblastic Lymphoma/Leukemia

  • Precursor Lymphoid Neoplasm

  • Leukemia, Acute Lymphoblastic, Susceptibility To

  • B-Cell Acute Lymphoblastic Leukemia

  • Leukemia, Acute Lymphocytic 1

  • Acute Lymphocytic Leukaemia

  • Acute Lymphoblastic Leukemia/Lymphoma

  • All1

  • Childhood Acute Lymphoblastic Leukemia

  • Leukemia Acute Lymphoblastic 1

  • Leukemia Acute Lymphoblastic B-Hyperdiploid

  • Leukemia Acute Lymphocytic

  • Leukemia Acute Lymphocytic 1

  • Leukemia B-Cell Acute Lymphoblastic

  • Leukemia T-Cell Acute Lymphoblastic

  • Leukemia, Acute Lymphoblastic, 3

  • ALL3

  • Lymphoblastic Leukemia Acute

  • Leukemia, Acute, Lymphoblastic

  • Precursor Cell Lymphoblastic Leukemia Lymphoma

  • Leukemia, Lymphocytic, Acute, L1

  • Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Rhabdomyosarcoma
Tibial Nerve Palsy
Laryngeal Benign Neoplasm

  • Laryngeal Tumor

  • Larynx Neoplasm

  • Neoplasm Of Larynx

  • Laryngeal Cancer

  • Laryngeal Carcinoma

  • Cancer Of Larynx
Muscular Dystrophy

  • Muscular Dystrophies

  • Congenital Md

  • Congenital Muscular Dystrophy

  • Cmd

  • Mdc

  • Dystrophy, Muscular

  • Gower'S Muscular Dystrophy

  • Progressive Musclular Dystrophy

  • Pseudohypertrophic Atrophy

  • Pseudohypertrophic Muscle Paralysis

  • Pseudohypertrophic Muscular Atrophy

  • Pseudohypertrophic Muscular Dystrophy

  • Pseudohypertrophic Paralysis

  • Pseudomuscular Hypertrophy
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
Brain Glioma

  • Lower Grade Glioma

  • Intracranial Glioma

  • Glioma Nos
Colorectal Cancer, Hereditary Nonpolyposis, Type 8

  • HNPCC8

  • Hereditary Nonpolyposis Colorectal Cancer Type 8

  • Hereditary Non-Polyposis Colorectal Cancer 8

  • Cancer, Colorectal, Nonpolyposis, Hereditary, Type 8
Glioblastoma Classical Subtype
Malignant Astrocytoma

  • Astrocytic Tumor

  • Astrocytoma Of Brain

  • Astrocytoma Of Cerebrum

  • Astroglioma

  • Cerebral Astrocytoma

  • Astrocytoma
Esophageal Cancer

  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus
Gliosarcoma

  • Glioblastoma With Sarcomatous Component

  • Sarcomatous Glioblastoma
Severe Combined Immunodeficiency

  • Scid

  • Severe Combined Immunodeficiency Disease

  • Combined T And B Cell Inborn Immunodeficiency

  • Immunodeficiency, Severe Combined

  • Scid - [Severe Combined Immunodeficiencies]
Colonic Benign Neoplasm

  • Colon Neoplasm

  • Colonic Mass

  • Colonic Tumor

  • Neoplasm Of Colon

  • Neoplasm Of The Colon

  • Colonic Neoplasms

  • Colon Cancer

  • Colon Carcinoma Nos

  • Colonic Cancer

  • Metastatic Colon Cancer Nos
Leukemia, Acute Myeloid

  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Connective Tissue Disease

  • Connective Tissue Diseases

  • Connective Tissue Disorder

  • Abnormality Of Connective Tissue

  • Disorder Of Connective Tissue

  • Connective Tissue Disorders
Nervous System Disease

  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11198 PROM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17613 Prom1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24073 Prom1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991463 MS133 Inhibitor / Unkown
HY-P991431 Anti-CD133/PROM1 Antibody (CMab-43) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PROM1 RGD RGD:69367
Canis familiaris PROM1 VGNC VGNC:45012
Bos taurus PROM1 VGNC VGNC:33364
Macaca mulatta PROM1 VGNC VGNC:76425
Felis catus PROM1 VGNC VGNC:69079
Mus musculus PROM1 MGD MGI:1100886
Others PROM1 NCBI