2. Gene
  3. SRSF11 - serine and arginine rich splicing factor 11 Gene

SRSF11 - serine and arginine rich splicing factor 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as p54; NET2; SFRS11; dJ677H15.2

Gene ID: 9295 | Gene type: protein coding

About SRSF11

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:70,205,696-70,253,052 (from NCBI)

This gene has 18 transcripts (splice variants), 280 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 46.2), skin (RPKM 32.0) and 25 other tissues.

Summary

This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010]

SRSF11 Products(21)

mRNA Protein Name
NM_001190987.3 NP_001177916.1 serine/arginine-rich splicing factor 11 isoform 2
NM_001350605.2 NP_001337534.1 serine/arginine-rich splicing factor 11 isoform 1
NM_001350606.2 NP_001337535.1 serine/arginine-rich splicing factor 11 isoform 1
NM_001350607.2 NP_001337536.1 serine/arginine-rich splicing factor 11 isoform 2
NM_001350608.2 NP_001337537.1 serine/arginine-rich splicing factor 11 isoform 3
NM_001350609.2 NP_001337538.1 serine/arginine-rich splicing factor 11 isoform 4
NM_001350610.2 NP_001337539.1 serine/arginine-rich splicing factor 11 isoform 5
NM_001350611.2 NP_001337540.1 serine/arginine-rich splicing factor 11 isoform 6
NM_001350612.2 NP_001337541.1 serine/arginine-rich splicing factor 11 isoform 7
NM_001350613.2 NP_001337542.1 serine/arginine-rich splicing factor 11 isoform 7
NM_001350614.2 NP_001337543.1 serine/arginine-rich splicing factor 11 isoform 8
NM_001350615.2 NP_001337544.1 serine/arginine-rich splicing factor 11 isoform 8
NM_001350616.2 NP_001337545.1 serine/arginine-rich splicing factor 11 isoform 8
NM_001394402.1 NP_001381331.1 serine/arginine-rich splicing factor 11 isoform 9
NM_001394403.1 NP_001381332.1 serine/arginine-rich splicing factor 11 isoform 9
NM_001394404.1 NP_001381333.1 serine/arginine-rich splicing factor 11 isoform 3
NM_001394405.1 NP_001381334.1 serine/arginine-rich splicing factor 11 isoform 4
NM_001394406.1 NP_001381335.1 serine/arginine-rich splicing factor 11 isoform 1
NM_001394407.1 NP_001381336.1 serine/arginine-rich splicing factor 11 isoform 2
NM_001394408.1 NP_001381337.1 serine/arginine-rich splicing factor 11 isoform 2
NM_004768.5 NP_004759.1 serine/arginine-rich splicing factor 11 isoform 1

SRSF11 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (37 - 101)

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  • 484 a.a.
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 11

SR splicing factor 11

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13792 SRSF11 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SRSF11 VGNC VGNC:35299
Rattus norvegicus SRSF11 RGD RGD:1559953
Macaca mulatta SRSF11 VGNC VGNC:77818
Felis catus SRSF11 VGNC VGNC:65694
Canis familiaris SRSF11 VGNC VGNC:46817
Mus musculus SRSF11 MGD MGI:1916457