Glycothiohexide α
Glycothiohexide α is a peptide antibiotic. Glycothiohexide α has strong activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VREF), MIC values of 0.03-0.06 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 158446-31-2
- Formula: C58H57N13O15S6
- Molecular Weight:1368.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 158446-31-2
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Molecular Weight 1368.54
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Formula C58H57N13O15S6
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SMILES
O=C(C1=CSC(C2=C(C=C(C(C3=CSC(C(CSC(C(NC4=C5C(COC6=O)=CC=C4)=C5COC(C(C7=NC8=CS7)N9)C6O[C@H]%10C[C@](O)([C@@H]([C@@H](O%10)C)N(C)C)C)=O)NC8=O)=N3)=N2)C%11=NC(C(NC(C(C)O)C(N/C(C%12=NC(C9=O)=C(S%12)[H])=C(C)/OC)=O)=O)=CS%11)O)=N1)N
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Structure Classification
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Initial Source
"Sebekia" sp., LL-14E605
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)