Golidocitinib (Standard)
Golidocitinib (Standard) (AZD4205 (Standard)) is the analytical standard of Golidocitinib (HY-107361). This product is intended for research and analytical applications. Golidocitinib (AZD4205) is a selective JAK1 inhibitor, with an IC50 of 73 nM, weakly inhibits JAK2 (IC50>14.7 μM), and shows little inhibition on JAK3 (IC50>30 μM).
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- CAS. Nr.: 2091134-68-6
- Formel: C25H31N9O2
- Molecular Weight:489.57
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
IC50: 73 nM (JAK1), >14.7 μM (JAK2), >30 μM (JAK3)[1]
Chemical Information
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CAS. Nr. 2091134-68-6
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Molecular Weight 489.57
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Formel C25H31N9O2
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SMILES
C[C@@H](N1CCN(C)CC1)C(NC2=C3C(C(C4=NC(NC5=CN(C)N=C5OC)=NC=C4)=CN3)=CC=C2)=O
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Synonyms
AZD4205 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)