Golidocitinib (Standard)
Golidocitinib (Standard) (AZD4205 (Standard)) is the analytical standard of Golidocitinib (HY-107361). This product is intended for research and analytical applications. Golidocitinib (AZD4205) is a selective JAK1 inhibitor, with an IC50 of 73 nM, weakly inhibits JAK2 (IC50>14.7 μM), and shows little inhibition on JAK3 (IC50>30 μM).
For research use only. We do not sell to patients.
- CAS No.: 2091134-68-6
- Formula: C25H31N9O2
- Molecular Weight:489.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 73 nM (JAK1), >14.7 μM (JAK2), >30 μM (JAK3)[1]
Chemical Information
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CAS No. 2091134-68-6
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Molecular Weight 489.57
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Formula C25H31N9O2
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SMILES
C[C@@H](N1CCN(C)CC1)C(NC2=C3C(C(C4=NC(NC5=CN(C)N=C5OC)=NC=C4)=CN3)=CC=C2)=O
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Synonyms
AZD4205 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)