1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. GR 103691

GR 103691 

Cat. No.: HY-101382 Purity: >98.0%
Handling Instructions

GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites.

For research use only. We do not sell to patients.

GR 103691 Chemical Structure

GR 103691 Chemical Structure

CAS No. : 162408-66-4

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 224 In-stock
Estimated Time of Arrival: December 31
5 mg USD 210 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites[1].

IC50 & Target

Ki: 0.4 nM (Human dopamine D3 receptor)[1]

In Vitro

GR 103691 shows marked affinity for serotonin1A (5-HT1A) receptors (Ki of 5.8 nM) and α-1 adrenoceptors (Ki of 12.6 nM)[1].

Molecular Weight

485.62

Formula

C₃₀H₃₅N₃O₃

CAS No.

162408-66-4

SMILES

O=C(C1=CC=C(C2=CC=C(C(C)=O)C=C2)C=C1)NCCCCN3CCN(C4=CC=CC=C4OC)CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

Purity: >98.0%

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Keywords:

GR 103691GR103691GR-103691Dopamine ReceptorInhibitorinhibitorinhibit

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GR 103691
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