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  4. GSK248233A

GSK248233A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 1.03 μM and 2 nM, respectively. GSK248233A also shows activity against the AGC family. GSK248233A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays.

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GSK248233A Chemical Structure

GSK248233A Chemical Structure

CAS No. : 850665-21-3

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GSK248233A Related Antibodies

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Description

GSK248233A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 1.03 μM and 2 nM, respectively. GSK248233A also shows activity against the AGC family. GSK248233A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].

Molecular Weight

484.51

Formula

C25H24N8O3
CAS No.
SMILES

O=C(C1=CC=C(N(C)C)C=C1)NC2=CC(OC3=CC(N(CC)C(C4=NON=C4N)=N5)=C5C=N3)=CC=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK248233A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK248233A850665-21-3OthersInhibitorinhibitorinhibit

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