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Cat. No.: HY-185448

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HIV RT-IN-1

HIV RT-IN-1 is an inhibitor of HIV integrase and HIV reverse transcriptase-associated ribonuclease H. HIV RT-IN-1 is applicable to research related to HIV-1 infection.

For research use only. We do not sell to patients.

CAS No.: 1246741-36-5
Formula: C₁₉H₁₅NO₄
Molecular Weight:321.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

HIV RT-IN-1 Chemical Structure

CAS No.: 1246741-36-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Bioz

Biological Activity

Description

HIV RT-IN-1 is an inhibitor of HIV integrase and HIV reverse transcriptase-associated ribonuclease H. HIV RT-IN-1 is applicable to research related to HIV-1 infection^[1].

All HIV Isoforms :

In Vitro

HIV RT-IN-1 (compound 10u) inhibits HIV RT-associated ribonuclease H with an IC₅₀ value of 7.7 μM^[1].
HIV RT-IN-1 inhibits the strand transfer activity of HIV integrase with an IC₅₀ of 17 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1246741-36-5
Molecular Weight 321.33
Formula C₁₉H₁₅NO₄
SMILES

O=C(C1=CN(CC2=C(C3=CC=CC=C3)C=CC=C2)C=C(C1=O)O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kankanala J, et al. Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H. J Med Chem. 2016;59(10):5051-5062. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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HIV RT-IN-1

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HIV RT-IN-1 Related Classifications

HY-185448 Related Classifications