TC2
TC2 is an efficient GIPR-preferring monomeric quadruple agonist that can respectively activate GIPR, GLP-1R, GcgR, and Y2R with IC50 values of 0.47, 2.1, 30, and 55 nM respectively. TC2 exhibits a significant GLP-1R preference, with a significant reduction in β-inhibitory protein 2 (βArr2) recruitment, while maintaining a strong cAMP signal. TC2 can be used for research on obesity and diabetes.
For research use only. We do not sell to patients.
- Formula: C263H407N67O72
- Molecular Weight:5659.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Neuropeptide Y Receptor Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 5659.45
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Formula C263H407N67O72
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Sequence
Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Lys(γGlu-C16 acid)-Ser-Ile-Leu-Leu-Asp-Arg-Lys-Ala-Gln-Ala-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Leu-Arg-His-Tyr-Val-Asn-Trp-Leu-Thr-Arg-Gln-Arg-Tyr-NH2
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Sequence Shortening
Y-{Aib}-QGTFTSD-Lys(γGlu-C16 acid)-SILLDRKAQAAFIEYLLEGGPSLRHYVNWLTRQRY-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TC2 Related Classifications
HY-P11279 Related Classifications
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