Hydroxycelecoxib glucuronide
Hydroxycelecoxib glucuronide is the glucuronide metabolite of Celecoxib (HY-14398) and shows no activity in inhibiting COX-2 activity.
For research use only. We do not sell to patients.
- CAS No.: 264236-79-5
- Formula: C23H20F3N3O10S
- Molecular Weight:587.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Hydroxycelecoxib glucuronide is unstable under physiological pH conditions. It undergoes acyl migration to form β-glucuronidase-resistant positional isomers, and is converted to Carboxycelecoxib under the action of β-glucuronidase[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 264236-79-5
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Molecular Weight 587.48
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Formula C23H20F3N3O10S
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SMILES
FC(F)(C1=NN(C2=CC=C(C=C2)S(N)(=O)=O)C(C3=CC=C(C=C3)C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)=O)=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ma Y, et al. Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Sep 15;1001:202-11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydroxycelecoxib glucuronide Related Classifications
HY-W339278 Related Classifications
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