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Cat. No.: HY-N16974

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Hyperwightin B

Hyperwightin B is a Flavone (HY-N2424) derivative. Hyperwightin B can be isolated from Hypericum wightianum. Hyperwightin B does not exhibit significant neuroprotective activity against Corticosterone (HY-B1618)-induced neuronal injury.

For research use only. We do not sell to patients.

CAS No.: 2374723-86-9
Formula: C₂₀H₁₆O₆
Molecular Weight:352.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Hyperwightin B Chemical Structure

CAS No.: 2374723-86-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Hyperwightin B (10 μM; 48 h) does not show discernible neuroprotection in Corticosterone (HY-B1618)-injured PC12 cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:

poorly differentiated PC12 cells
Concentration:

10 μM (Hyperwightin B); 150 μM (corticosterone); 0.1% (v/v) (DMSO)
Incubation Time:

48 h (after 24 h initial culturing)
Result:

Exhibited no discernible neuroprotective activity at 10 μM against corticosterone-induced PC12 cell injury.
No explicit numerical viability value was reported.

Related Protocols :

Neurotoxicity Study

Chemical Information

CAS No. 2374723-86-9
Molecular Weight 352.34
Formula C₂₀H₁₆O₆
SMILES

OC1=C(C[C@H](O2)C(C)=C)C2=CC(OC(C3=CC(O)=C(C=C3)O)=C4)=C1C4=O
Structure Classification
- Flavonoids
- Flavones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Neethu V, et al. Green synthesis of silver nanoparticles (AgNPs) with Hypericum wightianum: Characterization and evaluation of its antibacterial activity, antioxidant activity and toxicity assessment on Artemia salina. Plant Science Today. 2025;12(3).

[2]. Yang L, et al. Phenolic constituents with neuroprotective activities from Hypericum wightianum. Phytochemistry. 2019 Sep;165:112049. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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