NIC
NIC is a host invasion inhibitor. NIC can suppress host invasion by interacting with the major invasion-related protein, merozoite surface protein 1 (MSP-1). NIC prevents the invasion of Plasmodium falciparum and Plasmodium vivax into the host.
For research use only. We do not sell to patients.
- CAS No.: 114773-20-5
- Formula: C15H16ClN3O3
- Molecular Weight:321.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Biological Activity
Description
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 114773-20-5
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Molecular Weight 321.76
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Formula C15H16ClN3O3
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SMILES
O=CC1=C(N=C(CCCC)N1CC2=CC=C([N+]([O-])=O)C=C2)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell invasion
Cell invasion is the ability of cells to migrate from one area to another via the extracellular matrix. Cell invasion is the response of normal and cancer cells to chemical and mechanical stimuli. Before migrating to a new region, the extracellular matrix is degraded by proteases within the cell. Cell invasion often occurs during wound repair, vascularization and inflammation, abnormal tissue invasion, and tumor cell metastasis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NIC Related Classifications
HY-124078 Related Classifications
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