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IDO1/TDO-IN-8

IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor that can penetrate the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. IDO1/TDO-IN-8 reduces the kynurenine/tryptophan ratio by regulating the kynurenine pathway of tryptophan metabolism. IDO1/TDO-IN-8 has a neuroprotective effect and can alleviate motor dysfunction and improve depressive behavior. IDO1/TDO-IN-8 can be used in the study of Parkinson's disease combined with depression.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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  • CAS 番号: 3085413-22-2
  • 分子式: C17H14N2S
  • 分子量:278.37
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • IDO1/TDO-IN-8 Chemical Structure
    IDO1/TDO-IN-8 構造式
CAS 番号: 3085413-22-2
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  • IDO1/TDO-IN-8 Chemical Structure
    IDO1/TDO-IN-8 Chemical Structure
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  • IDO1/TDO-IN-8