NDNA4

NDNA4 (compound 17) is a selective inhibitor of Hsp90α (IC50: 0.34 μM). NDNA4 is a permanently charged analog with low membrane permeability and low cytotoxicity against Ovcar-8 and MCF-10A ((IC50 >100 μM)). NDNA4 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90α-dependent client proteins.

For research use only. We do not sell to patients.

  • Formula: C31H35F3N2O5S
  • Molecular Weight:604.68
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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