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Cat. No.: HY-187834

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Inositol 4-phosphate

Name: Inositol 4-phosphate
Brand: MedChemExpress
SKU: HY-187834
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(Synonyms: IP1)

Inositol 4-phosphate (IP1) is an inositol monophosphate isomer derived from the dephosphorylation of I(1,4)P₂. Inositol 4-phosphate increases rapidly in GH3 cells after thyrotropin-releasing hormone stimulation. Inositol 4-phosphate can be used in glioma-related research.

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CAS No.: 46495-39-0
Formule: C₆H₁₃O₉P
Masse moléculaire:260.13

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Please store the product under the recommended conditions in the Certificate of Analysis.

Inositol 4-phosphate Chemical Structure

CAS No.: 46495-39-0

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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Endogenous Metabolite :

In Vitro

Inositol 4-phosphate (IP₁) accumulates in C6 glioma cells in a time- and concentration-dependent manner upon histamine stimulation (EC₅₀ = 4.1 μM)^[1].
Inositol 4-phosphate (I4P) accumulates in GH₃ cells following TRH stimulation; its levels rise rapidly within 30 s and continue to increase for up to 30 min; moreover, it is separable from other inositol phosphate isomers using anion-exchange HPLC^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Endocrine Diseases

Chemical Information

CAS No. 46495-39-0
Masse moléculaire 260.13
Formule C₆H₁₃O₉P
SMILES

O(P(=O)(O)O)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
Synonyms

IP1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Tseng CL, et al. Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. Journal of the Chinese Medical Association : JCMA. 2012 Apr;75(4):143-50.

[2]. Shyng SL, et al. Membrane phospholipid control of nucleotide sensitivity of KATP channels. Science. 1998 Nov 6;282(5391):1138-41.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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