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Cat. No.: HY-146073

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IRAK4-IN-12

IRAK4-IN-12 (compound 37) is a potent IRAK4 inhibitor with an IC₅₀ of 0.015 µM. IRAK4-IN-12 shows cell pIRAK4 potencies with an IC₅₀ of 0.5 µM.

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Formule: C₂₄H₃₁FN₈O
Masse moléculaire:466.55

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

IRAK4-IN-12 Chemical Structure

Stock

Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IRAK4-IN-12 (compound 37) is a potent IRAK4 inhibitor with an IC₅₀ of 0.015 µM. IRAK4-IN-12 shows cell pIRAK4 potencies with an IC₅₀ of 0.5 µM^[1].

IC₅₀ & Target

^[1]

IRAK4

0.015 μM (IC₅₀)

Voir tous les produits spécifiques à Isoform IRAK :

Chemical Information

Masse moléculaire 466.55
Formule C₂₄H₃₁FN₈O
SMILES

F[C@@H](CN1C=CC2=C(C(NC3(CC3)C)=NC(NC4=CN(N=C4)C5CC6(CN(C6)C)C5)=N2)C1=O)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Cumming IA, et al. Identification and optimisation of a pyrimidopyridone series of IRAK4 inhibitors. Bioorg Med Chem. 2022 Jun 1;63:116729. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

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Quantité:

IRAK4-IN-12

Voir tous les produits spécifiques à Isoform IRAK

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

IRAK4-IN-12 Related Classifications

HY-146073 Related Classifications

Bioz

Keywords

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