IDT307
Based on 3 publication(s) in Google Scholar
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+).
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 1141-41-9
- Formula: C14H17IN2
- Molecular Weight:340.20
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) IDT307
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Biological Activity
IDT307, an analog of the organic cation MPP+, is transported into CP epithelial cells at the apical (CSF-facing) membrane and sensitive to inhibition by the PMAT inhibitor quinine[1].
IDT307 uptake and intracellular accumulation is greatly attenuated by ~70% in CP tissue from the Pmat knockout mouse[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 1141-41-9
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Appearance Solid
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Molecular Weight 340.20
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Formula C14H17IN2
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Color Yellow to orange
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SMILES
C[N+]1=CC=C(C2=CC=C(N(C)C)C=C2)C=C1.[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (3)
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Journal Impact Factor
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Most Recent
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Acta Pharmacol Sin
Esflurbiprofen exerts a fast-onset antidepressant effect by blocking SERT-nNOS interaction. [Abstract]2025 Oct 9. PMID: 41068287 -
J Med Chem
Development of Novel Estradiol-Indole Hybrids Targeting SERT and ERβ as Potential Antidepressants. [Abstract]2026 Jun 11;69(11):13618-13634. PMID: 42154662 -
J Ethnopharmacol
The allyl isothiocyanate (AITC) isolated from mustard (Sinapis alba L.) oil exerts antidepressant effects by blocking the interaction between SERT and nNOS. [Abstract]2026 Feb 28:357:120876. PMID: 41274522
Solvent & Solubility
DMSO : 62.5 mg/mL (183.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (479 KB)
- English - EN (479 KB)
- Français - FR (479 KB)
- Deutsch - DE (479 KB)
- Norwegian - NO (479 KB)
- Español - ES (479 KB)
- Swedish - SV (479 KB)
- Italian - IT (479 KB)
- Korean - KR (479 KB)
- Portuguese - PT (479 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9394 mL | 14.6972 mL | 29.3945 mL | 73.4862 mL |
| 5 mM | 0.5879 mL | 2.9394 mL | 5.8789 mL | 14.6972 mL | |
| 10 mM | 0.2939 mL | 1.4697 mL | 2.9394 mL | 7.3486 mL | |
| 15 mM | 0.1960 mL | 0.9798 mL | 1.9596 mL | 4.8991 mL | |
| 20 mM | 0.1470 mL | 0.7349 mL | 1.4697 mL | 3.6743 mL | |
| 25 mM | 0.1176 mL | 0.5879 mL | 1.1758 mL | 2.9394 mL | |
| 30 mM | 0.0980 mL | 0.4899 mL | 0.9798 mL | 2.4495 mL | |
| 40 mM | 0.0735 mL | 0.3674 mL | 0.7349 mL | 1.8372 mL | |
| 50 mM | 0.0588 mL | 0.2939 mL | 0.5879 mL | 1.4697 mL | |
| 60 mM | 0.0490 mL | 0.2450 mL | 0.4899 mL | 1.2248 mL | |
| 80 mM | 0.0367 mL | 0.1837 mL | 0.3674 mL | 0.9186 mL | |
| 100 mM | 0.0294 mL | 0.1470 mL | 0.2939 mL | 0.7349 mL |
IDT307 Related Classifications
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