KIN-8741
KIN-8741 is a highly selective Type IIb c-Met inhibitor. KIN-8741 has broad activity against c-Met kinase mutations. KIN-8741 shows antitumor activity in MET gene amplified and exon 14 deleted non-small cell lung cancer models. KIN-8741 can be used in the research of c-Met driven cancers, especially advanced tumors carrying MET exon 14 jump mutations, acquired drug resistance mutations, etc.
For research use only. We do not sell to patients.
- CAS No.: 2941104-53-4
- Formula: C26H23F2N3O6
- Molecular Weight:511.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2941104-53-4
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Molecular Weight 511.47
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Formula C26H23F2N3O6
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SMILES
FC1=CC(NC(C2=C(C=CN=C2)OC)=O)=CC(F)=C1OC3=CC=NC4=CC(OC)=C(C=C43)O[C@H](CO)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)