SNAP 398299
SNAP 398299 is a Gal3 receptor antagonist with potential anxiolytic and antidepressant effects. SNAP 398299 can partially reverse the neuropeptide Galanin-induced inhibition of dorsal raphe cell firing and the Galanin-induced hyperpolarizing current.
For research use only. We do not sell to patients.
- CAS No.: 903878-06-8
- Formula: C27H24F3N3O2
- Molecular Weight:479.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Galectin Isoforms
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Biological Activity
Chemical Information
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CAS No. 903878-06-8
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Molecular Weight 479.49
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Formula C27H24F3N3O2
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SMILES
O=C1/C(C2=CC=CC=C2N1C3=CC(OCCN4CCCC4)=CC=C3)=N/C5=CC=CC(C(F)(F)F)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Swanson CJ, et al. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. [Content Brief]
[2]. Insights of structure-based pharmacophore studies and inhibitor design against Gal3 receptor through molecular dynamics simulations [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)