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Cat. No.: HY-153744

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JGK-068S

JGK-068S (compound I) is a potent EGFR inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2490431-16-6
Formula: C₂₂H₂₃BrFN₅O₂
Molecular Weight:488.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

JGK-068S Chemical Structure

CAS No.: 2490431-16-6

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Top Publications Citing

Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

JGK-068S (compound I) is a potent EGFR inhibitor^[1].

IC₅₀ & Target^[1]

EGFR

All EGFR Isoforms :

Chemical Information

CAS No. 2490431-16-6
Molecular Weight 488.35
Formula C₂₂H₂₃BrFN₅O₂
SMILES

CN(CC1)CCN1C[C@@H]2OC3=CC(C(NC4=C(C(Br)=CC=C4)F)=NC=N5)=C5C=C3OC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fritz Blatter, et al. Egfr inhibitor polymorph forms. WO2023049312A1.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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