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C14-490

C14-490, an ionizable cationic lipid (pKa = 5.94), is used for the synthesis of lipid nanoparticles (LNPs). C14-490 LNPs is used as the basis for subsequent study of in utero gene editing in HSCs. C14-490 LNPs are used to encapsulate SpCas9 mRNA and TTR sgRNA using optimized B5 formulation parameters and surface conjugation to CD45 antibody F(ab’)2 fragments-Systematically optimized Targeted Editing Machinery LNPs (STEM LNPs).

For research use only. We do not sell to patients.

  • CAS No.: 2639634-82-3
  • Formula: C86H177N5O7
  • Molecular Weight:1393.35
  • Storage:

    Solution, -20°C, 2 years

  • C14-490 Chemical Structure
    C14-490 Chemical Structure
CAS No.: 2639634-82-3
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    C14-490 Chemical Structure
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  • C14-490