Oxphaman
Oxphaman is a pea lipoxygenase inhibitor with an IC50 of 140 nM against pea lipoxygenase. Oxphaman inhibits protamine sulfate-induced degranulation of rat peritoneal mast cells.
For research use only. We do not sell to patients.
- CAS No.: 112851-89-5
- Formula: C17H21NO2
- Molecular Weight:271.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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lipoxygenase 140 nM (IC50) |
Oxphaman (ZIMET 47/79) inhibits purified pea lipoxygenase activity with an IC50 of 1.4×10-4 mol/L[1].
Oxphaman (5 minutes prior to protamine sulfate activation) inhibits protamine sulfate-induced degranulation of peritoneal rat mast cells with an IC50 of 3.4×10-5 mol/L[1].
Oxphaman (2.5×10-4-5×10-4 mol/L; 5 minutes prior to Triton X-100 activation) weakly inhibits Triton X-100-induced degranulation of peritoneal rat mast cells, with 26.0% inhibition at 5×10-4 mol/L and 13.9% inhibition at 2.5×10-4 mol/L[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 112851-89-5
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Molecular Weight 271.35
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Formula C17H21NO2
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SMILES
OC1=CC=C(C(/C=N/C23CC4CC(C3)CC(C2)C4)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Oxphaman Related Classifications
HY-183237 Related Classifications
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