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Sym004

Customer Review

Based on 1 Customer Validation

Sym004 is a 1:1 mixture of two recombinant, human-mouse chimeric mAbs directed against nonoverlapping EGFR epitopes (mAb992 and mAb1024). Sym004 is ability to mediate rapid EGFR internalization and subsequent degradation of internalized receptors via EGFR cross-linking. Sym004 can be used for the study of metastatic colorectal cancer, head and neck (H&N) and lung cancer.

For research use only. We do not sell to patients.

  • Purity: 98.97%
  • Molecular Weight:146.269 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sym004
  • Sym004 Chemical Structure
    Sym004 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Sym004 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All EGFR Isoforms

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100 mg

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Assay Types
  • 1/16

    Immobilized EGFR Protein, Human (Active, sf9, His-GST, HY-P72987) can bind Sym004. The EC50 for this effect is 20.91 ng/mL.

  • Sym004 Chemical Structure
    1/16
  • Sym004
  • Immobilized EGFR Protein, Human (Active, sf9, His-GST, HY-P72987) can bind Sym004. The EC50 for this effect is 20.91 ng/mL.