country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-32735C

Copy Link Print Information

(14R)-Triptolide

(別名: (14R)-PG490)

(14R)-Triptolide ((14R)-PG490) (Compound T59) is a Triptolide (HY-32735) derivative. (14R)-Triptolide shows anti-cancer activity against multiple cancer cells with IC₅₀ of 0.477-2.53 μM. (14R)-Triptolide can be used for the research of cancer, such as ovarian cancer and colon cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 144539-79-7
分子式: C₂₀H₂₄O₆
分子量:360.40

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

(14R)-Triptolide 構造式

CAS 番号: 144539-79-7

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.059 μg/mL Compound: 11	Cytotoxicity against human A549 lung tumor cells Cytotoxicity against human A549 lung tumor cells	[PMID: 16455242]
A549	IC₅₀	59 ng/mL Compound: 1b, 14-epi-triptolide	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 18321701]
HT-29	IC₅₀	0.0091 μg/mL Compound: 11	Cytotoxicity against human HT29 colon tumor cells Cytotoxicity against human HT29 colon tumor cells	[PMID: 16455242]
HT-29	IC₅₀	9.1 ng/mL Compound: 1b, 14-epi-triptolide	Cytotoxicity against human HT29 cells Cytotoxicity against human HT29 cells	[PMID: 18321701]
MDA-MB-468	IC₅₀	1.32 μM Compound: 2	Cytotoxicity against human MDA-MB-468 cells by SRB assay Cytotoxicity against human MDA-MB-468 cells by SRB assay	[PMID: 19637874]
PC-3	IC₅₀	1.6 μM Compound: 2	Cytotoxicity against human PC3 cells by SRB assay Cytotoxicity against human PC3 cells by SRB assay	[PMID: 19637874]
PC-3	IC₅₀	1320 nM Compound: 2	Cytotoxicity against human PC3 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells after 72 hrs by sulforhodamine B assay	[PMID: 24378709]
SK-OV-3	IC₅₀	0.79 μM Compound: 2	Cytotoxicity against human SKOV3 cells by SRB assay Cytotoxicity against human SKOV3 cells by SRB assay	[PMID: 19637874]
SK-OV-3	IC₅₀	790 nM Compound: 2	Cytotoxicity against human SKOV3 cells after 72 hrs by sulforhodamine B assay Cytotoxicity against human SKOV3 cells after 72 hrs by sulforhodamine B assay	[PMID: 24378709]

化学情報

CAS 番号 144539-79-7
分子量 360.40
分子式 C₂₀H₂₄O₆
SMILES

C[C@@]12[C@@]34[C@]5([C@H]([C@@]6([C@](O6)([H])[C@]3([H])O4)C(C)C)O)[C@@](C[C@@]1([H])C7=C(C(OC7)=O)CC2)([H])O5
別名

(14R)-PG490
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (273 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. DanYang, et al. Polycyclic epoxides and compositions thereof with anti-cancer activities. WO2016181312A1. 2017-11-11

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ