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2-NBDG

74 Cited Publications
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Based on 74 publication(s) in Google Scholar

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.

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  • 純度: 99.74%
  • CAS 番号: 186689-07-6
  • 分子式: C12H14N4O8
  • 分子量:342.26
  • 保管条件:

    -20°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • 2-NBDG Chemical Structure
    2-NBDG 構造式
  • Experimental Validation Results for 2-NBDG
  • Experimental Validation Results for 2-NBDG
  • Experimental Validation Results for 2-NBDG
  • Experimental Validation Results for 2-NBDG
  • Experimental Validation Results for 2-NBDG
  • Experimental Validation Results for 2-NBDG
CAS 番号: 186689-07-6
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  • 2-NBDG Chemical Structure
    2-NBDG Chemical Structure
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    2-NBDG purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2022 Apr 19;2022:4608914. [Abstract]

    Customer Validation
     H9c2 cells are incubated with 2-NBDG (50 μM; for 30 min). Flow cytometry quantified the 2-NBDG signals in HG-stimulated H9c2 cells.

  • 1/16

    2-NBDG purchased from MedChemExpress. Usage Cited in: Food Funct. 2021 Mar 21;12(6):2726-2740. [Abstract]

    Customer Validation
     Glucose absorption and photomicrographs of HepG2 cells stained with 2-NBDG (100 μM; for 30 min).

  • 1/16

    2-NBDG purchased from MedChemExpress. Usage Cited in: J Cell Physiol. 2021 Aug;236(8):5818-5831. [Abstract]

    Customer Validation
     The cells are treated with 10 μM 2‐NBDG in serum‐free DMEM/F12 for 30 min.

  • 1/16

    2-NBDG purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2021 Jun 27;2021:5549047. [Abstract]

    Customer Validation
     Immunofluorescence images results of glucose uptake in glioblastoma cells determined by staining with 2-NBDG (50 μM; for 30 min) after treated with TGF-β1 in the absence or presence of GKT137831.

  • 1/16

    2-NBDG purchased from MedChemExpress. Usage Cited in: Mar Drugs. 2020 Sep 22;18(9):485. [Abstract]

    Customer Validation
     Caco-2 cells are treated with 100 μM 2‐NBDG for 30 min. Only 400 μg/mL of an AnF solution could significantly inhibit the transport of 2-NBDG in this Caco-2 monolayer cell model compared with the Control group, while the same concentration of LjF and KcF could not.

  • 1/16

    2-NBDG purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2021 Oct 5;2021:8542809. [Abstract]

    Customer Validation
     3T3-L1 are incubated with or without media containing 10 nM insulin for 10 minutes. The media are changed to low-glucose DMEM containing 150 μg/mL 2-NBDG for 60 minutes at 37°C.

  • 2-NBDG