4′-DTMP
Based on 1 Customer Validation
4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFRWT) and 34.3 nM (DHFRL28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 21253-58-7
- 分子式: C13H16N4O3
- 分子量:276.30
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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eDHFR |
化学情報
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CAS 番号 21253-58-7
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性状 Solid
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分子量 276.30
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分子式 C13H16N4O3
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Color Light brown to brown
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SMILES
OC1=C(OC)C=C(CC2=CN=C(N)N=C2N)C=C1OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (180.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6193 mL | 18.0963 mL | 36.1925 mL | 90.4814 mL |
| 5 mM | 0.7239 mL | 3.6193 mL | 7.2385 mL | 18.0963 mL | |
| 10 mM | 0.3619 mL | 1.8096 mL | 3.6193 mL | 9.0481 mL | |
| 15 mM | 0.2413 mL | 1.2064 mL | 2.4128 mL | 6.0321 mL | |
| 20 mM | 0.1810 mL | 0.9048 mL | 1.8096 mL | 4.5241 mL | |
| 25 mM | 0.1448 mL | 0.7239 mL | 1.4477 mL | 3.6193 mL | |
| 30 mM | 0.1206 mL | 0.6032 mL | 1.2064 mL | 3.0160 mL | |
| 40 mM | 0.0905 mL | 0.4524 mL | 0.9048 mL | 2.2620 mL | |
| 50 mM | 0.0724 mL | 0.3619 mL | 0.7239 mL | 1.8096 mL | |
| 60 mM | 0.0603 mL | 0.3016 mL | 0.6032 mL | 1.5080 mL | |
| 80 mM | 0.0452 mL | 0.2262 mL | 0.4524 mL | 1.1310 mL | |
| 100 mM | 0.0362 mL | 0.1810 mL | 0.3619 mL | 0.9048 mL |
4′-DTMP 関連分類
HY-W587663 関連分類
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