5-OH-DPAT
5-OH-DPAT (5-Hydroxy-DPAT) is a potent and selective dopamine D2-receptor agonist lacking effects at 5-HT receptors. 5-OH-DPAT produces a moderate facilitation of the male rat sexual behavior.
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- CAS 番号: 68593-96-4
- 分子式: C16H25NO
- 分子量:247.38
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Dopamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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D2 Receptor |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| AtT20 | EC50 |
1.23 nM
Compound: 5-OH-DPAT
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Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding
Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding
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[PMID: 20038106] |
化学情報
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CAS 番号 68593-96-4
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分子量 247.38
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分子式 C16H25NO
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SMILES
OC1=CC=CC2=C1CCC(N(CCC)CCC)C2
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別名
5-Hydroxy-DPAT
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ahlenius S, et al. Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat. Naunyn Schmiedebergs Arch Pharmacol. 1989 May;339(5):551-6. [Content Brief]
[2]. Karlsson A, et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): assessment of optical purities and dopaminergic activities. Chirality. 1990;2(2):90-5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
5-OH-DPAT 関連分類
HY-131531A 関連分類
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