6-Hydroxyindole (Standard)
6-Hydroxyindole (Standard) is the analytical standard of 6-Hydroxyindole (HY-W002438). This product is intended for research and analytical applications. 6-Hydroxyindole is an orally active, endogenous long-acting OATP1B1 inhibitor. 6-Hydroxyindole does not alter the cell surface expression or subcellular localization of OATP1B1. 6-Hydroxyindole protects cells against Ferroptosis. 6-Hydroxyindole possesses intrinsic radical-trapping antioxidant activity. 6-Hydroxyindole serves as a component of oxidative hair dyes. 6-Hydroxyindole can be used in research related to renal failure and neurodegenerative diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2380-86-1
- 分子式: C8H7NO
- 分子量:133.15
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 2380-86-1
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分子量 133.15
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分子式 C8H7NO
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SMILES
OC1=CC2=C(C=C1)C=CN2
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Masuo Y, et al. 6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients. Drug Metab Pharmacokinet. 2020;35(6):555-562. [Content Brief]
[2]. Jakaria M, et al. The role of hydroxyindoles in protecting neuronal cultures from ferroptosis. Cell Death Discov. 2025;11(1):329. Published 2025 Jul 16. [Content Brief]
[3]. Burnett CL, et al. Safety assessment of 6-hydroxyindole as used in cosmetics. Int J Toxicol. 2014;33(3 Suppl):24S-35S. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- 6-Hydroxyindole (Standard)
- 2380-86-1
- Reference Standards
- Biochemical Assay Reagents
- Endogenous Metabolite
- OAT
- Ferroptosis
- glutathione
- HT-22 mouse hippocampal neurons
- OATP1B1
- HEK293/OATP1B1 cells
- organic anion transporting polypeptide 1B1
- blood-brain barrier
- N27 rat dopaminergic neurons
- neurodegenerative diseases
- renal failure
- ferroptosis
- Inhibitor
- inhibitor
- inhibit