9(S)-HODE
Based on 1 Customer Validation
9(S)-HODE (Alpha-dimorphecolic acid) is the major active derivative of Linoleic acid (HY-N0729). 9(S)-HODE regulates the expression of miR-361-3p. 9(S)-HODE reduces cancer cell viability and induces cancer cell apoptosis. 9(S)-HODE can be used in the research of acute myeloid leukemia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98%
- CAS 番号: 73543-67-6
- 分子式: C18H32O3
- 分子量:296.44
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保管条件:
Solution, -20°C, 2 years
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
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Human Endogenous Metabolite |
9S-HODE (12.5-25 μM; 12-72 h) significantly downregulates the expression of miR-361-3p in HL-60 cells[1].
9S-HODE (25 μM; 0-72 h) inhibits the viability of HL-60 cells and induces apoptosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human acute myeloid leukemia HL-60 cells
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Concentration:25 μM
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Incubation Time:12, 24, 36, 48, 72 h
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Result:Downregulated miR-361-3p expression in a time-dependent manner.
Increased BTG2 mRNA expression.
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Cell Line:human acute myeloid leukemia HL-60 cells
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Concentration:25 μM
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Incubation Time:48 h
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Result:Increased the percentages of early apoptotic (Annexin V+/PI-) and late apoptotic (Annexin V+/PI+) HL-60 cells compared to control.
化学情報
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CAS 番号 73543-67-6
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性状 Liquid
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分子量 296.44
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分子式 C18H32O3
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O
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別名
Alpha-dimorphecolic acid
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Solution, -20°C, 2 years
純度とドキュメンテーション
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データシート (265 KB)
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SDS (544 KB)
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- Italian - IT (544 KB)
- Korean - KR (544 KB)
- Portuguese - PT (544 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)