ERB-196
Based on 1 Customer Validation
ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.89%
- CAS 番号: 550997-55-2
- 分子式: C17H10FNO2
- 分子量:279.27
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
ERβ[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 550997-55-2
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性状 Solid
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分子量 279.27
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分子式 C17H10FNO2
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Color Light brown to brown
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SMILES
N#CC1=C2C=C(O)C=CC2=CC(C3=CC=C(O)C(F)=C3)=C1
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別名
WAY-202196
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
Ethanol : 16 mg/mL (57.29 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
The neutropenic rat model of pseudomonas sepsis are used in this study. For the survival study, ERB-196 (50 mg/kg; n=12) or vehicle control (n=8) is administered daily by orogastric feeding beginning on day 4 after the first dose of cyclophosphamide and continuing for 8 days. Animals are assessed clinically and pathologically by measuring daily body weight, body temperature, presence of bacteremia, circulating endotoxin levels, and pathologic evidence of damage to the gastrointestinal epithelium and liver by light microscopy and electron microscopy. Blood and tissue samples are serially diluted in sterile saline and incubated at 37°C on pseudomonas agar for quantitative assessment of bacterial concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 3.5808 mL | 17.9038 mL | 35.8076 mL | 89.5191 mL |
| 5 mM | 0.7162 mL | 3.5808 mL | 7.1615 mL | 17.9038 mL | |
| 10 mM | 0.3581 mL | 1.7904 mL | 3.5808 mL | 8.9519 mL | |
| 15 mM | 0.2387 mL | 1.1936 mL | 2.3872 mL | 5.9679 mL | |
| 20 mM | 0.1790 mL | 0.8952 mL | 1.7904 mL | 4.4760 mL | |
| 25 mM | 0.1432 mL | 0.7162 mL | 1.4323 mL | 3.5808 mL | |
| 30 mM | 0.1194 mL | 0.5968 mL | 1.1936 mL | 2.9840 mL | |
| 40 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2380 mL | |
| 50 mM | 0.0716 mL | 0.3581 mL | 0.7162 mL | 1.7904 mL |
ERB-196 関連分類
HY-19468 関連分類
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