NNC45-0781
NNC45-0781 is a tissue-selective estrogen partial-agonist.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 207277-66-5
- 分子式: C27H29NO3
- 分子量:415.52
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Estrogen Receptor[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Ishikawa | EC50 |
0.9 nM
Compound: (+/-)cis 5
|
Stimulation of alkaline phosphatase activity in Ishikawa human endometrial adenocarcinoma cells
Stimulation of alkaline phosphatase activity in Ishikawa human endometrial adenocarcinoma cells
|
[PMID: 11738564] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 207277-66-5
-
分子量 415.52
-
分子式 C27H29NO3
-
SMILES
OC1=CC=C([C@@H](C2=CC=C(OCCN3CCCC3)C=C2)[C@@H](C4=CC=CC=C4)CO5)C5=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
Rats[1]
Female Sprague-Dawley rats, 12 weeks of age, weighing approximately 250 g are used in these studies.The pharmacological properties of NNC45-0781 (NNC 45-0781) are studied through a series of in vivo experiments. Activity of orally administered NNC45-0781 (1,10, 50 and 100 nmol/g) on total serum cholesterol in the ovariectomized rat.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)