Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
参考文献:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
All Product Categories
-
Drug Intermediate 関連製品 (4538)
関連製品 (4538)
-
L-Lactic acid sodium
(乳酸ナトリウム)
0 Images別名: Sodium L-lactate; Sodium (S)-2-hydroxypropanoateL-lactate Sodium (Sodium (S)-2-hydroxypropanoate) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity.
-
Fmoc-Arg(Pbf)-OH
(Fmoc-Arg(Pbf)-OH)
0 ImagesFmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis).
-
tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate
![tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate](https://file.medchemexpress.com/product_pic/hy-30536.gif "Click to View tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate Product Detail")
0 Imagestert-Butyl 3,9-diazaspiroundecane-3-carboxylate is a 3,9-diazaspiroundecane-based building block and precursor for synthesizing γ-aminobutyric acid type A (GABAA) receptor antagonists.
-
4-Aminobenzyl alcohol
(4-Aminobenzyl alcohol)
0 Images別名: 4-アミノベンジルアルコール4-Aminobenzyl alcohol is a self-eliminating linker. 4-Aminobenzyl alcohol can be used to synthesize the fluorescent probe MB-Van1 targeting Vanin-1.
-
Boc-3,3-DicPr-Ala-OH
0 Images製品番号: HY-W453851CAS 番号: 2548967-22-0
-
2,5-Dihydroxyterephthalic acid
0 Images製品番号: HY-W004616CAS 番号: 610-92-42,5-Dihydroxyterephthalic acid is a carboxylic acid ligand with antioxidant properties, which serves as a building block for Zn2+-based metal-organic frameworks (MOFs). 2,5-Dihydroxyterephthalic acid forms stable coordination bonds with transition metal ions, inhibits metal center-water coordination to prevent MOF fluorescence quenching, and enhances the hydrophilicity of MOFs. 2,5-Dihydroxyterephthalic acid acts as a pharmaceutical intermediate to synthesize 2,5-dihydroxyterephthalamide derivatives. 2,5-Dihydroxyterephthalic acid is applicable to relevant research in fields such as organic synthesis.
-
2-(Bromomethyl)acrylic acid
0 Images製品番号: HY-W017180CAS 番号: 72707-66-5別名: α-(Bromomethyl)acrylic acid; α-Methylated acrylamide; α-MAA
-
HPMC (Viscosity:11250-21000mPa.s)
0 Images別名: Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
-
UDP-glucuronic acid trisodium
(UDP-glucuronic acid (trisodium))
0 Images別名: ウリジン-5'-ジホスホグルクロン酸三ナトリウムUDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
-
(R)-5,7-Difluorochroman-4-ol
0 Images(R)-5,7-Difluorochroman-4-ol is a drug intermediate for synthesis of various active compounds.
-
Sirpiglenastat
0 Images別名: DRP-104Sirpiglenastat (DRP-104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response.
-
DBU
0 ImagesDBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic sterically hindered amidine with strong basicity, which possesses multiple properties such as nucleophilicity and coordination ability. DBU is prone to hydrolysis and can undergo addition, substitution, cyclization and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst.
-
Exatecan Intermediate 2
0 ImagesExatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers.
- Triazabicyclodecene (Triazabicyclodecene)
-
tert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate
![tert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate](https://file.medchemexpress.com/product_pic/hy-w054424.gif "Click to View tert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl)carbamate Product Detail")
0 Imagestert-Butyl (3-aminobicyclo[1.1.1]pentan-1-yl) carbamate is a pharmaceutical intermediate used in the synthesis of various active compounds, such as for the preparation of tetrazole-based eIF2B activators.
-
4-Chloro-6,7-dimethoxyquinoline
0 Images別名: Oro-6,7-dimethoxyquinol4-Chloro-6,7-dimethoxyquinoline (Oro-6,7-dimethoxyquinol) is a drug intermediate for synthesis of various active compounds.
-
tBu2bpy
0 ImagestBu2bpy is a bidentate nitrogen ligand that coordinates with Pt (II) and Pt (IV) to form functional complexes. The tBu2bpy Pt (II) bis-crown ether complex selectively recognizes Mg2+ and Zn2+; both ions significantly enhance the fluorescence of the complex and cause a blue shift of the absorption peak. Its six-coordinate Pt (IV) complex [Pt (X)2Me2 (tBu2bpy)] inhibits the proliferation of tumor cells. tBu2bpy Pt (IV) complexes bind to DNA through multiple interactions including partial intercalation, groove binding, and electrostatic interaction, and can competitively displace ethidium bromide and covalently bind to purine nucleotides. tBu2bpy can be used in relevant research in fields such as organic synthesis.
-
6-Chloropyrimidine-4-carboxylic acid
0 Images6-Chloropyrimidine-4-carboxylic acid is a drug intermediate for synthesis of various active compounds.
