UK-240455
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 178908-09-3
- 分子式: C11H11Cl2N3O5S
- 分子量:368.19
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
生物活性
-
化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
iGluR アイソフォーム固有の製品をすべて表示
More
生物活性
|
NMDA Receptor |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 178908-09-3
-
分子量 368.19
-
分子式 C11H11Cl2N3O5S
-
SMILES
CS(=O)(N(C1=C(Cl)C(Cl)=CC(NC2=O)=C1NC2=O)CCO)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
UK-240455 is administered both i.v. and orally at a dose of 2 mg/kg to male rats. Before and during the i.v. and oral studies, animals have free access to food and water. For i.v. studies, UK-240455 is administered to rats (250 to 300 g) via the tail vein. At the following time points (n=3/time point) blood samples are taken under terminal anaesthesia: predose, 0.1, 0.25, 0.5, 1.0, 1.5, 2.0, 4.0 and 7.0 h postdose. Blood samples are collected into heparinized tubes and centrifuged to separate plasma. The plasma is removed and stored frozen. Three further rats are dosed with UK-240455 as above and placed in metabolism cages to collect urine. After 24 h, these animals are killed and the urine collected and stored frozen[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Powered by Bioz