ABCA1 inducer 2

ABCA1 inducer 2 (Compound 3) (0.01-10 μM, 24 h) has a strong ability to activate the ABCA1 promoter in Hela cells^[1].
ABCA1 inducer 2 (0.01-10 μM, 18 h) effectively induces the expression of ABCA1 mRNA in RAW 264.7 cells in a dose-dependent manner, with the maximum increase at 10 μM being 3.94-fold of that in the control group^[1].
ABCA1 inducer 2 (0.01-10 μM, 12-48 h) upregulates ABCA1 protein expression in RAW 264.7 cells and Hela cells by acting on the LXR pathway^[1].
ABCA1 inducer 2 (10 μM, 24 h) can effectively reduce ox-LDL-induced intracellular lipid accumulation and inhibit the formation of foam cells in RAW 264.7 cells^[1].
ABCA1 inducer 2 (10 μM, 48 h) induces limited lipid and triglyceride accumulation in HepG2 cells, reduces adverse effects associated with hypertriglyceridemia and hepatic lipogenesis^[1].
ABCA1 inducer 2 (0.01-10 μM, 24 h) has no significant toxicity to Hela, RAW264.7 and HepG2 cells at a concentration of 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.