ACG416B
Based on 1 Customer Validation
ACG416B (compound 18) is a potent inhibitor of ChoK (choline kinase) with an IC50 of 0.4 μM. ACG416B renders higher ChoK inhibitory and antiproliferative activities against the HT-29 human colon cancer cell.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.99%
- CAS 番号: 795316-15-3
- 分子式: C38H36Br2N4
- 分子量:708.53
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
ChoK[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
2.2 μM
Compound: 18
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Antiproliferative activity was determined using HT-29 human colon cancer cell line
Antiproliferative activity was determined using HT-29 human colon cancer cell line
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[PMID: 15481981] |
化学情報
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CAS 番号 795316-15-3
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性状 Solid
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分子量 708.53
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分子式 C38H36Br2N4
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Color White to off-white
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SMILES
CN(C1=CC=[N+](CC2=CC(C3=CC=CC(C[N+]4=CC=C(N(C)C5=CC=CC=C5)C=C4)=C3)=CC=C2)C=C1)C6=CC=CC=C6.[Br-].[Br-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (141.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4114 mL | 7.0569 mL | 14.1137 mL | 35.2843 mL |
| 5 mM | 0.2823 mL | 1.4114 mL | 2.8227 mL | 7.0569 mL | |
| 10 mM | 0.1411 mL | 0.7057 mL | 1.4114 mL | 3.5284 mL | |
| 15 mM | 0.0941 mL | 0.4705 mL | 0.9409 mL | 2.3523 mL | |
| 20 mM | 0.0706 mL | 0.3528 mL | 0.7057 mL | 1.7642 mL | |
| 25 mM | 0.0565 mL | 0.2823 mL | 0.5645 mL | 1.4114 mL | |
| 30 mM | 0.0470 mL | 0.2352 mL | 0.4705 mL | 1.1761 mL | |
| 40 mM | 0.0353 mL | 0.1764 mL | 0.3528 mL | 0.8821 mL | |
| 50 mM | 0.0282 mL | 0.1411 mL | 0.2823 mL | 0.7057 mL | |
| 60 mM | 0.0235 mL | 0.1176 mL | 0.2352 mL | 0.5881 mL | |
| 80 mM | 0.0176 mL | 0.0882 mL | 0.1764 mL | 0.4411 mL | |
| 100 mM | 0.0141 mL | 0.0706 mL | 0.1411 mL | 0.3528 mL |
ACG416B 関連分類
HY-122675 関連分類
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