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AKIR001

カスタマーレビュー

Based on 1 Customer Validation

AKIR001 is a high-affinity human IgG1 antibody targeting CD44v6. AKIR001 carries LALA-silencing mutations in its FcγR-binding domain to reduce FcγR and C1q interactions, minimizing tissue interactions and limiting CDC and ADCC risks. [177Lu] radiolabeled AKIR001, namely [177Lu]Lu-AKIR001, has anticancer activity against epidermoid carcinoma.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.41%
  • 分子量:145.48 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for AKIR001
  • Experimental Validation Results for AKIR001
  • AKIR001 Chemical Structure
    AKIR001 構造式
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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  • 1/16

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  • 1/16

    Immobilized Human CD44v6 Protein can bind AKIR001. The ED50 for this effect is 86.8 ng/mL.

  • AKIR001 Chemical Structure
    1/16
  • AKIR001
  • Immobilized Human CD44v6 Protein can bind AKIR001. The ED50 for this effect is 86.8 ng/mL.
  • Product Image