AM-5262
AM-5262 is a GPR40 full agonist with an EC50 value of 0.081 μM. AM-5262 can be used for the research of type II diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1222088-90-5
- 分子式: C33H35FO4
- 分子量:514.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
EC50: 0.081 μM (GPR40)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
0.081 μM
Compound: 26, AM-5262
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Agonist activity at human FFA1 receptor expressed in CHO cell membranes after 4 hrs by aequorin bioluminescence assay
Agonist activity at human FFA1 receptor expressed in CHO cell membranes after 4 hrs by aequorin bioluminescence assay
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[PMID: 24900707] |
AM-5262 has activity for GPR40 with an EC50 value of 0.081 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
AM-5262 (0-100 μM) enhances glucose stimulated insulin secretion (mouse and human islets) and improves glucose homeostasis in vivo (OGTT in HF/STZ mice) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1222088-90-5
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分子量 514.63
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分子式 C33H35FO4
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SMILES
COC1=CC=C(F)C(C2=C([C@@H]3CCCC3(C)C)C=C(COC4=CC=C(CC[C@]56C[C@]6(C(O)=O)[H])C5=C4)C=C2)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AM-5262 関連分類
HY-16619 関連分類
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