Anticancer agent 301
Anticancer agent 301 is an anticancer agent. Anticancer agent 301 selectively downregulates the phosphorylation level of ERK1/2 without affecting the NF-κB p65 subunit. Anticancer agent 301 exhibits antiproliferative activity against breast cancer cells and can be used in breast cancer-related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C20H18N2O2
- 分子量:318.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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ERK1 |
ERK2 |
Anticancer agent 301 potently inhibits proliferation of MCF-7 human breast cancer cells with an IC50 of 15.34 ± 0.17 μM[1].
Anticancer agent 301 (12.5-100 μM) selectively inhibits ERK1/2 phosphorylation in MCF-7 human breast cancer cells at 25 μM, without affecting NF-κB p65 phosphorylation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 318.37
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分子式 C20H18N2O2
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SMILES
O=C(N1CCC2=C(NC3=CC=CC=C32)C1)/C=C/C4=CC=C(C=C4)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)