AR-12463
AR-12463 is a derivative of Trapidil (HY-B1016). AR-12463 inhibits the conversion of [14C]acetate to cholesterol. AR-12463 significantly reduces the elevation of total cholesterol in rabbit serum and prevents cholesterol incorporation into tissues. AR-12463 can be used to study atherosclerosis.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 100557-04-8
- 分子式: C17H28N6O
- 分子量:332.44
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 100557-04-8
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分子量 332.44
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分子式 C17H28N6O
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SMILES
OCCN(CCCCC)C1=CC(N2CCCCC2)=NC3=NC=NN31
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Beitz J, et al. Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits. Biomed Biochim Acta. 1991;50(1):101-7. PMID: 1859385. [Content Brief]
[2]. Beitz J, et al. Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits. Biomed Biochim Acta. 1991;50(1):101-7. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)