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Blinatumomab

(別名: bscCD19xCD3; AMG-103; MEDI-538; MT-103; BLINCYTO)
3 Cited Publications
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Based on 3 publication(s) in Google Scholar

Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia.

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  • 純度: 97.33%
  • CAS 番号: 853426-35-4
  • 分子量:54.09 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Blinatumomab
  • Experimental Validation Results for Blinatumomab
  • Experimental Validation Results for Blinatumomab
  • Experimental Validation Results for Blinatumomab
  • Blinatumomab Chemical Structure
    Blinatumomab 構造式
CAS 番号: 853426-35-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    (scFv-kappa-heavy)-(scFv-heavy-kappa)

  • 1/16

    Loaded Blinatumomab on CM5 Chip, can bind CD19 Protein, Human (CHO, Fc, HY-P7333) with an affinity constant of 11.02E-9 M as determined in SPR assay.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Blinatumomab (HY-P9963). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • 1/16

    Blinatumomab purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 Jun 18;5(6):101590. [Abstract]

    Customer Validation
     Histogram of the percentage of conjugated cells when 2 × 105 Dye 670-stained NY-ESO-1157-165-primed HLA-A∗0201-Raji cells were cocultured 1 h with mixed 2 × 104 CFSE-stained 1G4-PD-1-Jurkat cells and 2 × 104 Dye 450-stained PD-1-Jurkat cells. The concentration of αPD-1-(iRGD)2 was 10 μg/mL, while Blinatumomab (1 μg/mL; 1 h) .

  • Blinatumomab Chemical Structure
    1/16
  • Blinatumomab
  • Loaded Blinatumomab on CM5 Chip, can bind CD19 Protein, Human (CHO, Fc, HY-P7333) with an affinity constant of 11.02E-9 M as determined in SPR assay.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Blinatumomab (HY-P9963). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • (scFv-kappa-heavy)-(scFv-heavy-kappa)