BPN-01
BPN-01 is a fluorescent probe targeting translocator protein (TSPO) and human epidermal growth factor receptor 2 (HER2) with binding affinities of -10.7 kcal/mol for TSPO and -11.3 kcal/mol for HER2. BPN-01 is promising for research of solid tumor imaging during fluorescence image-guided surgery (FIGS) (Ex/Em = 475/510 nm).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C22H16N6O5S
- 分子量:476.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
BPN-01 (3.91 μg/mL, 7.81 μg/mL, 15.63 μg/mL, 31.25 μg/mL, 62.5 μg/mL, 125 μg/mL, 250 μg/mL, 500 μg/mL; 48 h; B16-F10) maintains B16-F10 cell viability at ~100% across all concentrations[1].
BPN-01 (0.01 mM, 0.05 mM, 0.1 mM, 0.5 mM, 1.0 mM; 24 h; DU-145, B16-F10, C2C12) stains DU-145 and B16-F10 cancer cells at 0.01 mM but not at higher concentrations or in C2C12 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 476.46
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分子式 C22H16N6O5S
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SMILES
COC1=CC=C2C(SC(C(NC3=CC=C(C=C3)CNC4=CC=C(C5=NON=C45)[N+]([O-])=O)=O)=N2)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BPN-01 関連分類
HY-172534 関連分類
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