CJ28
Based on 1 Customer Validation
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.21%
- CAS 番号: 3047118-54-4
- 分子式: C14H11BrN4O
- 分子量:331.17
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
Cortisol biosynthesis[1]
化学情報
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CAS 番号 3047118-54-4
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性状 Solid
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分子量 331.17
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分子式 C14H11BrN4O
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Color White to off-white
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SMILES
O=C(NC1=NC2=CC=CC=C2N1)NC3=CC(Br)=CC=C3
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (150.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0196 mL | 15.0980 mL | 30.1960 mL | 75.4899 mL |
| 5 mM | 0.6039 mL | 3.0196 mL | 6.0392 mL | 15.0980 mL | |
| 10 mM | 0.3020 mL | 1.5098 mL | 3.0196 mL | 7.5490 mL | |
| 15 mM | 0.2013 mL | 1.0065 mL | 2.0131 mL | 5.0327 mL | |
| 20 mM | 0.1510 mL | 0.7549 mL | 1.5098 mL | 3.7745 mL | |
| 25 mM | 0.1208 mL | 0.6039 mL | 1.2078 mL | 3.0196 mL | |
| 30 mM | 0.1007 mL | 0.5033 mL | 1.0065 mL | 2.5163 mL | |
| 40 mM | 0.0755 mL | 0.3774 mL | 0.7549 mL | 1.8872 mL | |
| 50 mM | 0.0604 mL | 0.3020 mL | 0.6039 mL | 1.5098 mL | |
| 60 mM | 0.0503 mL | 0.2516 mL | 0.5033 mL | 1.2582 mL | |
| 80 mM | 0.0377 mL | 0.1887 mL | 0.3774 mL | 0.9436 mL | |
| 100 mM | 0.0302 mL | 0.1510 mL | 0.3020 mL | 0.7549 mL |