Claramine
Claramine is a steroid polyamine with blood-brain barrier permeability. Claramine can regulate the properties of lipid membranes and protect cells from various biological toxins, including misfolded protein oligomers and biological protein-based toxins.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1430194-56-1
- 分子式: C37H72N4O
- 分子量:588.99
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
Claramine (2-20 μM; 20 h) does not affect cell viability in human neuroblastoma cells (SH-SY5Y) at concentrations below 10 μM. Similarly, Claramine (2-20 μM; 20 h) does not impact cell activity in HEK293 cells[1].
Claramine (2.5-10 μM; 20 h) protects human neuroblastoma (SH-SY5Y) cells from the harmful effects of pore-forming agents, melittin (HY-P0233) (4 μM; 20 h) and α-hemolysin (50 μg/mL; 20 h), by inhibiting their binding to cell membranes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1430194-56-1
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分子量 588.99
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分子式 C37H72N4O
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SMILES
C[C@@]12[C@]3([H])[C@](C[C@H](C1([H])C[C@H](CC2)O)NCCCNCCCCNCCCN)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Claramine 関連分類
HY-160791 関連分類
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