Clostripain
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Clostripain (Clostridiopeptidase B) is a thiol protease isolated from Clostridium histolyticum. Clostripain exhibits proteolytic activity as well as amidase-esterase activity. The specificity of Clostripain is primarily restricted to arginine residues, but it also shows minor hydrolytic activity toward most lysine-containing substrates. Clostripain catalyzes the ammonolysis of Carbobenzoxyarginyl methyl ester to generate various dipeptides.
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- CAS 番号: 9028-00-6
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
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Microbial Metabolite |
Clostripain exhibits proteolytic activity as well as amidase-esterase activity. Its specificity is primarily restricted to arginine residues, but it also shows minor hydrolytic activity toward most lysine-containing substrates[1].
Clostripain catalyzes the ammonolysis of Carbobenzoxyarginyl methyl ester to produce a variety of dipeptides[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
3.4.22.8
≥50 U/mg soild
One unit is defined as the amount of enzyme that will hydrolyze 1.0 μmole of BAEE per min at pH 7.6 at 25°C in the presence of 2.5 mM DTT.
化学情報
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CAS 番号 9028-00-6
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性状 Solid
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Color White to off-white
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SMILES
[Clostripain]
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別名
Clostridiopeptidase B
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (266 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Mitchell WM, et al. Purification and properties of clostridiopeptidase B (Clostripain). J Biol Chem. 1968 Sep 25;243(18):4683-92. [Content Brief]
[2]. Fortier G, et al. Kinetic study of nucleophile specificity in dipeptide synthesis catalyzed by clostridiopeptidase B. Arch Biochem Biophys. 1990;276(2):317-321. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Clostripain 関連分類
HY-P2895 関連分類
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