Corticosterone-d4
Based on 1 Customer Validation
Corticosterone-d4 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.17%
- CAS 番号: 2243253-91-8
- 分子式: C21H26D4O4
- 分子量:350.49
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 2243253-91-8
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非標識Cas 50-22-6
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性状 Solid
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分子量 350.49
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分子式 C21H26D4O4
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Color White to off-white
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SMILES
C[C@@]12[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([2H])[C@](O)([2H])C2([2H])[2H])=O
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別名
17-Deoxycortisol-d4; 11β,21-Dihydroxyprogesterone-d4; Kendall's compound B-d4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (285.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 14.29 mg/mL (40.77 mM; Need ultrasonic)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26(34):8758-8766. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 2.8531 mL | 14.2657 mL | 28.5315 mL | 71.3287 mL |
| 5 mM | 0.5706 mL | 2.8531 mL | 5.7063 mL | 14.2657 mL | |
| 10 mM | 0.2853 mL | 1.4266 mL | 2.8531 mL | 7.1329 mL | |
| 15 mM | 0.1902 mL | 0.9510 mL | 1.9021 mL | 4.7552 mL | |
| 20 mM | 0.1427 mL | 0.7133 mL | 1.4266 mL | 3.5664 mL | |
| 25 mM | 0.1141 mL | 0.5706 mL | 1.1413 mL | 2.8531 mL | |
| 30 mM | 0.0951 mL | 0.4755 mL | 0.9510 mL | 2.3776 mL | |
| 40 mM | 0.0713 mL | 0.3566 mL | 0.7133 mL | 1.7832 mL | |
| DMSO | 50 mM | 0.0571 mL | 0.2853 mL | 0.5706 mL | 1.4266 mL |
| 60 mM | 0.0476 mL | 0.2378 mL | 0.4755 mL | 1.1888 mL | |
| 80 mM | 0.0357 mL | 0.1783 mL | 0.3566 mL | 0.8916 mL | |
| 100 mM | 0.0285 mL | 0.1427 mL | 0.2853 mL | 0.7133 mL |
Corticosterone-d4 関連分類
HY-B1618S1 関連分類
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