CRT0063465
Based on 1 Customer Validation
CRT0063465 is a Ligand of HumanPGK1andStress Sensor DJ1, with theKdof 24 μM ofPGK1. CRT0063465 modulates the shelterin complex composition and telomere Length.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.64%
- 分子式: C17H16BrN3O2
- 分子量:374.23
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Anti-Cancer Compound Library
HY-L025
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Anti-diabetic Compound Library
HY-L040
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Metabolic Enzyme Compound Library
HY-L146
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
CRT0063465 (10 nM, 1 week) modulates the composition of shelterin complexes in unstressed HCT116 cells[1].
CRT0063465 (100 nM, up to 100 h) has protective effect against Bleomycin (HY-17565)-induced cytotoxicity in A2780 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Solid
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分子量 374.23
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分子式 C17H16BrN3O2
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Color Off-white to light yellow
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SMILES
CC1=C(CCC(O)=O)C(C)=NC2=CC(C3=CC=C(Br)C=C3)=NN12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 20 mg/mL (53.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6722 mL | 13.3608 mL | 26.7215 mL | 66.8038 mL |
| 5 mM | 0.5344 mL | 2.6722 mL | 5.3443 mL | 13.3608 mL | |
| 10 mM | 0.2672 mL | 1.3361 mL | 2.6722 mL | 6.6804 mL | |
| 15 mM | 0.1781 mL | 0.8907 mL | 1.7814 mL | 4.4536 mL | |
| 20 mM | 0.1336 mL | 0.6680 mL | 1.3361 mL | 3.3402 mL | |
| 25 mM | 0.1069 mL | 0.5344 mL | 1.0689 mL | 2.6722 mL | |
| 30 mM | 0.0891 mL | 0.4454 mL | 0.8907 mL | 2.2268 mL | |
| 40 mM | 0.0668 mL | 0.3340 mL | 0.6680 mL | 1.6701 mL | |
| 50 mM | 0.0534 mL | 0.2672 mL | 0.5344 mL | 1.3361 mL |
CRT0063465 関連分類
HY-153917 関連分類
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