Cyanidin
Based on 5 publication(s) in Google Scholar
Cyanidin is an orally active antioxidant and enzyme inhibitor. Cyanidin has IC50 values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin can be used in the research of inflammatory diseases.
It is advisable to consider the similar product (Cyanidin Chloride) that retains the same biological activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 13306-05-3
- 分子式: C15H11O6+
- 分子量:287.24
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 Cyanidin
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生物活性
製品説明
体外実験
Cyanidin (2 μM; 21 min) inhibits lipid peroxidation in a liposomal model system with 57% inhibition at 2 μM, showing antioxidant activity comparable to commercial antioxidants BHA and BHT and superior to vitamin E[2].
Cyanidin (5-30 μM) scavenges DPPH radicals in a concentration-dependent manner[3].
Cyanidin (0.1-1 μM) scavenges O2− radicals in a concentration-dependent manner[3].
Cyanidin (100-400 μM) protects DNA from H2O2-induced damage[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 13306-05-3
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分子量 287.24
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分子式 C15H11O6+
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SMILES
OC1=CC2=[O+]C(C3=CC=C(O)C(O)=C3)=C(O)C=C2C(O)=C1
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Food Res Int
Slow starch digestion in the rice cooked with adzuki bean: Contribution of procyanidins and the oxidation products. [Abstract]2019 May:119:187-195. PMID: 30884648 -
Int Immunopharmacol
IL-17A/IL-17RA interaction blockade sensitizes synovial macrophages to efferocytosis and PD-L1 signaling via rewiring STAT-3/ADAM17/MERTK axis in rheumatoid arthritis animal model. [Abstract]2024 Jul 30:136:112343. PMID: 38810305 -
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Hum Cell
Long noncoding RNA XIST modulates microRNA-135/CREB1 axis to influence osteogenic differentiation of osteoblast-like cells in mice with tibial fracture healing. [Abstract]2022 Jan;35(1):133-149. PMID: 34635983 -
純度とドキュメンテーション
参考文献
[1]. Noda Y, et al. Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin. J Agric Food Chem. 2002;50(1):166-171. [Content Brief]
[2]. Wang H, et al. Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod. 1999;62(2):294-296. [Content Brief]
[3]. Acquaviva R, et al. Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage protectors and antioxidants. Cell Biol Toxicol. 2003 Aug;19(4):243-52. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)